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首页> 外文期刊>Journal of biomedical materials research. Part B, Applied biomaterials. >Fabrication of reactive poly(vinyl alcohol) membranes for prevention of bone cement leakage
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Fabrication of reactive poly(vinyl alcohol) membranes for prevention of bone cement leakage

机译：制备反应性聚乙烯醇膜以防止骨水泥渗漏

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Leakage of bone cement into the spinal canal has been reported to cause many adverse effects. In this study, we designed an implantable balloon kyphoplasty material that avoids cement leakage through the formation of covalent bonds with the bone cement. For this purpose, glycidyl methacrylate (GMA) was used as a reactive functional group attached to the poly(vinyl alcohol) (PVA) membrane. The prepared membrane adhered to poly(methyl methacrylate) (PMMA)-based bone cements within 10 min, which is the time required for PMMA polymerization in the bone cement. The bonding strength between the GMA PVA membrane and the PMMA-based bone cement was higher than that for the original PVA membrane, likely because vinyl bonds form between the surface of the GMA PVA membrane and the bone cement. Since the GMA PVA membrane adhered firmly to the PMMA-based bone cement, the membrane was able to completely cover the PMMA-based bone cement. (C) 2014 Wiley Periodicals, Inc.
机译：据报道，骨水泥渗入椎管会引起许多不利影响。在这项研究中，我们设计了一种可植入的球囊后凸成形术材料，该材料可通过与骨水泥形成共价键来避免水泥泄漏。为此，使用甲基丙烯酸缩水甘油酯（GMA）作为附着在聚乙烯醇（PVA）膜上的反应性官能团。制备的膜在10分钟内粘附到基于聚甲基丙烯酸甲酯（PMMA）的骨水泥上，这是PMMA在骨水泥中聚合所需的时间。 GMA PVA膜和基于PMMA的骨水泥之间的结合强度高于原始PVA膜，这可能是因为在GMA PVA膜的表面和骨水泥之间形成了乙烯基键。由于GMA PVA膜牢固地粘附在基于PMMA的骨水泥上，因此该膜能够完全覆盖基于PMMA的骨水泥。 （C）2014威利期刊公司

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