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Oxygen, water, and sodium chloride transport in soft contact lenses materials

机译:柔软隐形眼镜材料中的氧气,水和氯化钠运输

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Abstract Oxygen permeability, diffusion coefficient of the sodium ions and water flux and permeability in different conventional hydrogel (Hy) and silicone‐hydrogel (Si‐Hy) contact lenses have been measured experimentally. The results showed that oxygen permeability and transmissibility requirements of the lens have been addressed through the use of siloxane containing hydrogels. In general, oxygen and sodium chloride permeability values increased with the water content of the lens but there was a percolation phenomenon from a given value of water uptake mainly in the Si‐Hy lenses which appeared to be related with the differences between free water and bound water contents. The increase of ion permeability with water content did not follow a unique trend indicating a possible dependence of the chemical structure of the polymer and character ionic and non‐ionic of the lens. Indeed, the salt permeability values for silicone hydrogel contact lenses were one order of magnitude below those of conventional hydrogel contact lenses, which can be explained by a diffusion of sodium ions occurring only through the hydrophilic channels. The increase of the ionic permeability in Si‐Hy materials may be due to the confinement of ions in nanoscale water channels involving possible decreased degrees of freedom for diffusion of both water and ions. In general, ionic lenses presented values of ionic permeability and diffusivity higher than most non‐ionic lenses. The tortuosity of the ionic lenses is lower than the non‐ionic Si‐Hy lenses. Frequency 55 and PureVision exhibited the highest water permeability and flux values and, these parameters were greater for ionic Si‐Hy lenses than for ionic conventional hydrogel lenses. ? 2016 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 105B: 2218–2231, 2017.
机译:摘要通过实验测量氧气渗透率,钠离子和水通量和水通量和渗透性的渗透率和硅氧烷 - 水凝胶(Si-HY)隐形眼镜的扩散系数。结果表明,通过使用含有水凝胶的硅氧烷来解决透镜的氧气渗透性和传动性要求。通常,氧气和氯化钠渗透率值随着镜片的含水量而增加,但是来自给定的水吸收的渗透现象主要是在Si-Hy晶状体中似乎与自由水和结合之间的差异有关。水含量。具有含水量的离子渗透性的增加未遵循独特的趋势,表明聚合物和晶状体的聚合物和非离子的化学结构的可能依赖性。实际上,硅氧烷水凝胶隐形眼镜的盐渗透值是低于常规水凝胶隐形眼镜的一个级,这可以通过仅通过亲水通道的钠离子的扩散来解释。 Si-Hy材料中的离子渗透性的增加可能是由于纳米级水通道中的离子的限制,涉及水和离子扩散的可能降低的自由度。通常,离子镜片呈现离子渗透性的值和高于大多数非离子镜片的扩散率。离子晶状体的曲折性低于非离子Si-Hy晶状体。频率55和pureVision表现出最高的水渗透性和助焊剂值,并且对于离子Si-Hy晶状体而言,这些参数比离子常规水凝胶透镜更大。还2016 Wiley期刊,INC.J生物保解员B:Appl Biomater,105B:2218-2231,2017。

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