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首页> 外文期刊>Journal of biomedical materials research. Part B, Applied biomaterials. >Inflammatory cell-induced corrosion in total knee arthroplasty: A retrieval study
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Inflammatory cell-induced corrosion in total knee arthroplasty: A retrieval study

机译：肿瘤间关节置换术中炎症细胞诱导的腐蚀：检索研究

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Metal release in patients with joint replacements is associated with local tissue reactions, pain, and ultimately revision of implants. One of the causes of this metal loss is speculated to be due to a mechanism of inflammatory cell-induced corrosion (ICIC). In this knee retrieval study, we aimed to: (1) identify the extent and location of ICI corrosion patterns on our femoral and tibial components and (2) correlate our findings with implant and clinical information. We investigated 28 femoral and 9 tibial components made of polished CoCr for presence of ICIC, using macroscopic and microscopic screening and statistical analyses to identify any significant correlations between our results and clinical information. We found that 71% of femoral and 100% of tibial components showed evidence of ICIC and significantly more was present on non-contacting regions (p0.0001). We found a significant correlation between the presence of ICIC and instability (p=0.0113) and a significant difference between poster stabilized and cruciate retaining designs in the amount of ICIC on internal edges (p=0.0375). This corrosion pattern was prevalent in our series of knee retrievals and may help explain some of the mechanisms of material loss that may occur in vivo. (c) 2016 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 106B: 460-467, 2018.
机译：关节置换患者的金属释放与局部组织反应，疼痛和最终修订植入物有关。推测这种金属损失的原因之一是由于炎症细胞诱导的腐蚀（ICIC）的机制。在这项膝盖检索研究中，我们的目标是：（1）确定ICI腐蚀模式对我们的股骨和胫骨成分的腐蚀模式的程度和位置，并将我们的研究结果与植入物和临床信息相关联。我们调查了由抛光COCR制成的28个股骨头和9个胫骨部件，用于使用宏观和微观筛选和统计分析来确定我们的结果和临床信息之间的任何显着相关性。我们发现71％的股骨头和100％的胫骨组分显示出ICIC的证据，并且在非接触区域上存在显着更多（P <0.0001）。我们发现ICIC和不稳定性（P = 0.0113）之间的存在性具有显着的相关性，并且海报之间的显着差异稳定并在内部边缘上的ICIC的量稳定并旋转设计（P = 0.0375）。这种腐蚀模式在我们的膝盖检索系列中普遍存在，并且可以帮助解释体内可能发生的一些物质损失机制。 （c）2016年Wiley期刊，Inc。J生物保解率B部分B：苹果生物摩特，106B：460-467，2018。

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