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首页> 外文期刊>Journal of biomedical materials research. Part B, Applied biomaterials. >FiberSecure suture compared to braided polyester suture
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FiberSecure suture compared to braided polyester suture

机译：纤维沉淀与编织聚酯缝合线相比

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Abstract Reliability of wound closure is limited primarily by the capacity of tissues to support conventional sutures (or staples), not by strength of either material per se . We developed FiberSecure? for closures to surpass tissue strength. We assessed and compared the mechanical and histological performance of FiberSecure? suture versus commercially available braided polyester suture (Mersilene) in the closure of abdominal muscle incisions in miniature swine at approximately 3?months postsurgery. Four incisions were closed in the external oblique muscle of eight Sinclair minipigs. Two wounds were closed with FiberSecure? suture size 0 and the remaining two with Mersilene suture size 0. At 90?days, specimens were removed for biomechanics and histology. In destructive tensile testing, in the 16 abdominal muscle specimens for the FiberSecure? suture, muscle tear was not near the suture implantation region, which remained intact. Wound strength met or exceeded strength of neighboring tissue in FiberSecure? groups, which had peak force of 55.7 ± 22.1 N (mean ± SD) and peak stress of 579.0 ± 159.2?KPa (mean ± SD). For Mersilene, 3 of the 16 samples tore at the suture site and the remaining samples tore through the abdominal muscle not near the implantation region. The wound strength was similar to surrounding tissue, and these specimens had peak force of 51.8 ± 21.7?N and peak stress of 550.3 ± 239.4?KPa (mean ± SD). No significant difference was observed in peak force or stress between groups ( p ??0.05), most repairs having met or exceeded native tissue strength by this time point. ? 2016 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 105B: 1126–1130, 2017.
机译：摘要伤口闭合的可靠性主要受到组织的能力，以支持常规缝合线（或钉），而不是通过本身的任何材料的强度。我们开发了纤维成本？用于关闭组织强度。我们评估并比较了纤维的机械和组织学表现？缝合线与商业上可获得的编织聚酯缝合线（Mersilene）在微型猪的腹部肌肉切口闭合，约3个月后期。在八个Sinclair Minipigs的外倾斜肌肉中关闭了四个切口。用纤维沉积封闭两个伤口？缝合尺寸0和剩余的两个具有塞利亚缝合线尺寸0.在90. 90？天，去除样品，用于生物力学和组织学。在破坏性的拉伸试验中，在16个腹部肌肉标本中的纤维型？缝合，肌肉撕裂不靠近缝合植入区域，仍然完好无损。缠绕强度在纤维的邻近组织达到或超过强度？峰值力为55.7±22.1n（平均值±SD）和579.0±159.2°（平均值±SD）的峰值力的峰值力。对于Mersilene，16个样品在缝合线部位的3个样品中的3个撕裂，并且剩余的样品通过腹部肌肉撕裂而不靠近植入区域。伤口强度类似于周围组织，这些样品的峰值力为51.8±21.7Ω，峰值应力为550.3±239.4 kPa（平均值±SD）。在峰值力或基团之间的峰值力或应力中没有观察到显着差异（P？＆Δ05），通过该时间点遇到或超过天然组织强度的大多数修理。还2016 Wiley期刊，Inc。J生物保解率B：苹果生物摩特，105B：1126-1130，2017。

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