Dabigatran etexilate in a vitamin-K antagonist non responder patient during Heartware HVAD support

Baronetto Andrea; Centofanti Paolo; Attisani Matteo; Boffini Massimo; Ricci Davide; Simonato Erika; Rinaldi Mauro

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Dabigatran etexilate in a vitamin-K antagonist non responder patient during Heartware HVAD support

机译：在Heartware HVAD支持期间，Dabigatran在维生素-K拮抗剂非响应者患者中乙酸盐

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We report a case of a patient supported with a HeartWare left ventricular assist device for idiopathic cardiomyopathy who was resistance to vitamin-K antagonists three months after implantation. The patient initially started low-molecular-weight heparin therapy and then, after the onset of an ischemic stroke, switched to dabigatran etexilate (DE). The patient had progressive recovery of cardiac function for which the device was explanted. No thrombotic or bleeding events occurred during DE therapy.

机译：我们举报了一种患者，该患者支持心脏软件左心室辅助装置，用于特发性心肌病，植入后三个月是对维生素-K拮抗剂的抵抗力。患者最初开始低分子量的肝素治疗，然后在缺血性卒中发生后，切换到Dabigatran eTexilate（de）。患者具有逐步恢复的心功能，其中介绍了该装置。在DE治疗期间没有发生血栓性或出血事件。

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来源
《Journal of cardiac surgery.》 |2017年第2期|共2页
作者
Baronetto Andrea; Centofanti Paolo; Attisani Matteo; Boffini Massimo; Ricci Davide; Simonato Erika; Rinaldi Mauro;
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作者单位

Univ Turin Div Cardiac Surg San Giovanni Battista Hosp Molinette Corso Bramanete 88-90 Turin;

Univ Turin Div Cardiac Surg San Giovanni Battista Hosp Molinette Corso Bramanete 88-90 Turin;

Univ Turin Div Cardiac Surg San Giovanni Battista Hosp Molinette Corso Bramanete 88-90 Turin;

Univ Turin Div Cardiac Surg San Giovanni Battista Hosp Molinette Corso Bramanete 88-90 Turin;

Univ Turin Div Cardiac Surg San Giovanni Battista Hosp Molinette Corso Bramanete 88-90 Turin;

Univ Turin Div Cardiac Surg San Giovanni Battista Hosp Molinette Corso Bramanete 88-90 Turin;

Univ Turin Div Cardiac Surg San Giovanni Battista Hosp Molinette Corso Bramanete 88-90 Turin;

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原文格式 PDF
正文语种 eng
中图分类心脏血管和淋巴系外科学;
关键词
dabigatran etexilate; heart failure; ventricular assist device;

机译：Dabigatran enexilate;心力衰竭;心室辅助装置;

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1. Dabigatran etexilate in a vitamin-K antagonist non responder patient during Heartware HVAD support [J] . Baronetto Andrea, Centofanti Paolo, Attisani Matteo, Journal of cardiac surgery. . 2017,第2期

机译：在Heartware HVAD支持期间，Dabigatran在维生素-K拮抗剂非响应者患者中乙酸盐
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3. A Pharmacokinetic Evaluation of Dabigatran Etexilate, Total Dabigatran, and Unconjugated Dabigatran Following the Administration of Dabigatran Etexilate Mesylate Capsules in Healthy Male and Female Subjects [J] . Bouhajib Mohammed, Tayab Zia Drug research . 2020,第1期

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机译：与达比尼妥兰坦的危险概况与老年人患者的维生素-K拮抗剂相比，非瓣膜心房颤动的维生素-K拮抗剂：法国全国索赔数据库的队列研究结果

Dabigatran etexilate in a vitamin-K antagonist non responder patient during Heartware HVAD support

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