Effects of prenatal alcohol consumption on cognitive development and ADHD-related behaviour in primary-school age: a multilevel study based on meconium ethyl glucuronide

Eichler Anna; Hudler Linda; Grunitz Juliane; Grimm Jennifer; Raabe Eva; Goecke Tamme W.; Fasching Peter A.; Beckmann Matthias W.; Kratz Oliver; Moll Gunther H.; Kornhuber Johannes; Heinrich Hartmut

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Effects of prenatal alcohol consumption on cognitive development and ADHD-related behaviour in primary-school age: a multilevel study based on meconium ethyl glucuronide

机译：产前醇消耗对小学时代认知发展和血清相关行为的影响：基于甲基葡萄糖醛酸甲基葡萄糖酮的多级研究

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BackgroundAlcohol intake during pregnancy is considered to be a risk factor for child development. Child biomarkers of intrauterine alcohol exposure have been rarely studied. We investigated whether a meconium alcohol metabolite (ethyl glucuronide, EtG) was associated with cognitive development, ADHD-related behaviour and neurophysiological markers of attention and executive control of children at primary-school age.

机译：妊娠期间的醇摄入被认为是儿童发展的危险因素。宫内酒精暴露的儿童生物标志物已经很少研究。我们调查了甲醇代谢物（乙基葡糖醛酸乙酯，ETG）是否与认知发育，ADHD相关的行为和神经生理学标志和小学时代儿童的执行控制有关。

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《Journal of child psychology and psychiatry》 |2018年第2期|共9页
作者
Eichler Anna; Hudler Linda; Grunitz Juliane; Grimm Jennifer; Raabe Eva; Goecke Tamme W.; Fasching Peter A.; Beckmann Matthias W.; Kratz Oliver; Moll Gunther H.; Kornhuber Johannes; Heinrich Hartmut;
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作者单位

Friedrich Alexander Univ Erlangen Nuremberg FAU Univ Hosp Erlangen Dept Child &

Adolescent Mental;

Friedrich Alexander Univ Erlangen Nuremberg FAU Univ Hosp Erlangen Dept Child &

Adolescent Mental;

Friedrich Alexander Univ Erlangen Nuremberg FAU Univ Hosp Erlangen Dept Child &

Adolescent Mental;

Friedrich Alexander Univ Erlangen Nuremberg FAU Univ Hosp Erlangen Dept Child &

Adolescent Mental;

Friedrich Alexander Univ Erlangen Nuremberg FAU Univ Hosp Erlangen Dept Obstet &

Gynecol;

Friedrich Alexander Univ Erlangen Nuremberg FAU Univ Hosp Erlangen Dept Obstet &

Gynecol;

Friedrich Alexander Univ Erlangen Nuremberg FAU Univ Hosp Erlangen Dept Obstet &

Gynecol;

Friedrich Alexander Univ Erlangen Nuremberg FAU Univ Hosp Erlangen Dept Obstet &

Gynecol;

Friedrich Alexander Univ Erlangen Nuremberg FAU Univ Hosp Erlangen Dept Child &

Adolescent Mental;

Friedrich Alexander Univ Erlangen Nuremberg FAU Univ Hosp Erlangen Dept Child &

Adolescent Mental;

Friedrich Alexander Univ Erlangen Nuremberg FAU Univ Hosp Erlangen Dept Psychiat &

Psychotherapy;

Friedrich Alexander Univ Erlangen Nuremberg FAU Univ Hosp Erlangen Dept Child &

Adolescent Mental;

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原文格式 PDF
正文语种 eng
中图分类医药、卫生;
关键词
Intrauterine alcohol exposure; ethyl glucuronide; meconium; alcohol; pregnancy; child; cognitive development; attention-deficit hyperactivity disorder; event-related potentials;

机译：宫内酒精曝光;葡萄糖醛酸乙酯;粉末;酒精;怀孕;儿童;认知发展;注意力缺陷多动障碍;事件相关的潜力;

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1. Effects of prenatal alcohol consumption on cognitive development and ADHD-related behaviour in primary-school age: a multilevel study based on meconium ethyl glucuronide [J] . Eichler Anna, Hudler Linda, Grunitz Juliane, Journal of child psychology and psychiatry . 2018,第2期

机译：产前醇消耗对小学时代认知发展和血清相关行为的影响：基于甲基葡萄糖醛酸甲基葡萄糖酮的多级研究
2. Quantification of fatty acid ethyl esters (FAEE) and ethyl glucuronide (EtG) in meconium for detection of alcohol abuse during pregnancy: Correlation study between both biomarkers [J] . Cabarcos Pamela, Jesus Tabernero Maria, Luis Otero Jose, Journal of Pharmaceutical and Biomedical Analysis: An International Journal on All Drug-Related Topics in Pharmaceutical, Biomedical and Clinical Analysis . 2014,第Null期

机译：胎粪中脂肪酸乙酯（FAEE）和葡萄糖醛酸乙酯（EtG）的定量检测在怀孕期间的酒精滥用：两种生物标记之间的相关性研究
3. Quantification of fatty acid ethyl esters (FAEE) and ethyl glucuronide (EtG) in meconium from newborns for detection of alcohol abuse in a maternal health evaluation study [J] . Bakdash A., Burger P., Goecke T.W., Analytical and bioanalytical chemistry . 2010,第7期

机译：从新生儿中定量脂肪酸乙酯（茯苓）和乙基葡糖醛酸乙酯（ETG），以检测孕产妇健康评估研究中的酒精滥用
4. Prenatal Bisphenol A Exposure and Cognitive and Behavioural Development in Children [C] . Martine Vrijheid, Maribel Casas, David Martinez, Annual conference of the International Society of Exposure Science . 2014

机译：产前双酚A暴露与儿童的认知和行为发展
5. Prevalence of Heavy Prenatal Alcohol Exposure in Uganda via Analysis of Fatty Acid Ethyl Esters in Meconium. [D] . Nightingale, Ira Justin. 2016

机译：通过分析胎粪中的脂肪酸乙基酯，分析乌干达产前重度酒精暴露的发生率。
6. Prenatal Alcohol Exposure and the Facial Phenotype in Adolescents: A Study Based on Meconium Ethyl Glucuronide [O] . Janina Maschke, Jakob Roetner, Tamme W. Goecke, 2021

机译：产前酒精暴露和青少年的面部表型：基于膀胱氨基葡萄糖醛酸的研究
7. Development and validation of a method for the simultaneous analysis of fatty acid ethyl esters, ethyl sulfate and ethyl glucuronide in neonatal meconium: application in two cases of alcohol consumption during pregnancy [O] . Mateusz Kacper Woźniak, Laura Banaszkiewicz, Justyna Aszyk, 2021

机译：新生儿型甲酸乙酯同时分析脂肪酸乙酯，乙基硫酸乙酯和乙基葡糖醛磷酸方法的开发及验证：在怀孕期间饮酒中的应用

Effects of prenatal alcohol consumption on cognitive development and ADHD-related behaviour in primary-school age: a multilevel study based on meconium ethyl glucuronide

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