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首页> 外文期刊>Journal of drugs in dermatology: JDD >Recommendations for Prevention of Drug Re-Exposure in Toxic Epidermal Necrolysis
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Recommendations for Prevention of Drug Re-Exposure in Toxic Epidermal Necrolysis

机译:预防药物重新暴露于有毒表皮坏死中的建议

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Drug re-exposure resulting in Stevens-Johnson syndrome (SJS) or toxic epidermal necrolysis (TEN) is a rare phenomenon and has scarcely been reported. With an aging population, polypharmacy, and a lack of a unified electronic medical record, standard recommendations to prevent or minimize the risk of re-exposure are necessary. We identified five patients, with diagnosis confirmed SJS/TEN, and determined the clinical characteristics and contributing risk factors leading to re-exposure. Polypharmacy, multiple prescribers, advanced age, medical illiteracy, retention of discontinued medications and self-prescribing all contributed to re-exposure in this cohort of patients. This case series demonstrates the potentially deadly effect of drug re-exposure, and the need for both streamlined and integrated medication allergy documentation systems.
机译:药物重新暴露导致史蒂文斯 - 约翰逊综合征(SJ)或有毒表皮坏死(十)是一种罕见的现象,几乎没有报道。 随着人口老龄化,复数和缺乏统一的电子医疗记录,需要预防或尽量减少重新暴露风险的标准建议是必要的。 我们鉴定了五名患者,诊断确认了SJS /十,并确定了临床特征和导致重新接触的危险因素。 多酚,多阶段,晚期年龄,医学文盲,停止的药物和自我规定的保留都有助于在这种患者队列中重新接触。 本案例系列证明了药物再暴露的潜在致命效果,以及精简和综合药物过敏文档系统的需求。

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