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Prevalence and Risk Factors of Acne Scarring Among Patients Consulting Dermatologists in the Unites States

机译:美国咨询皮肤科医生患者痤疮瘢痕的患病率和风险因素

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Although there have been few formal studies, scarring is a known bothersome companion of acne vulgaris. We performed a prospective study of subjects consulting a dermatologist for active acne to assess the frequency of acne scarring. Investigators performed a short questionnaire on all acne patients seen at their office for one consecutive 5-day work week to assess scar frequency. Additionally, the first four subjects with acne scars identified were enrolled for a second phase (scar cohort) of the study during which the investigator collected further medical history and performed a clinical evaluation and the patient completed a self-administered questionnaire about scar perceptions and impact on quality of life. A total of 1,972 subjects were evaluated by 120 investigators. Among these, 43% (n=843) had acne scarring. Subjects with acne scars were significantly more likely to have severe or very severe acne (P<.01); however, 69% of the subjects with acne scars had mild or moderate acne at the time of the study visit. Risk factors correlated with increased likelihood of scarring were acne severity, time between acne onset and first effective treatment, relapsing acne, and male gender. Treatments that can completely resolve acne scars are not yet available - prevention and early treatment remain a primary strategy against scars. It is vital for clinicians who manage individuals with acne to institute effective therapy as early as possible, since treatment delay is a key modifiable risk factor for scarring.
机译:虽然有很少的正式研究,但疤痕是痤疮狂欢的伴随痤疮的伴侣。我们对受试者进行了前瞻性研究,咨询了一种活性痤疮的皮肤科医生来评估痤疮疤痕的频率。调查人员在他们办公室的所有痤疮患者中进行了短暂的问卷,连续5天工作周,以评估瘢痕频率。另外,鉴定的前四个受试者鉴定了痤疮疤痕的研究,用于研究的第二阶段(Scar Cohort),其中调查员收集了进一步的病史并进行了临床评估,患者完成了关于瘢痕感知和影响的自我管理问卷论生活质量。通过120名调查人员评估总共1,972个受试者。其中,43%(n = 843)有痤疮疤痕。痤疮疤痕的受试者显着更容易具有严重或非常严重的痤疮(p <.01);然而,在研究访问时,69%的患有痤疮疤痕的受试者具有轻度或中度痤疮。危险因素与瘢痕形成的可能性增加是痤疮的严重程度,痤疮发作和首先有效治疗,复发痤疮和男性性别之间的时间。可以完全解决痤疮疤痕的治疗尚未提供 - 预防和早期治疗仍然是对伤疤的主要策略。尽早管理痤疮的临床医生至关重要,因为治疗延迟是疤痕的关键可修改的危险因素。

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