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首页> 外文期刊>Journal of cutaneous medicine and surgery >The Contribution of Malodour in Quality of Life of Patients With Hidradenitis Suppurativa
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The Contribution of Malodour in Quality of Life of Patients With Hidradenitis Suppurativa

机译：恶臭对Hidradenitisuptiva患者生活质量的贡献

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Background: Malodourous discharge in patients with hidradenitis suppurativa (HS) has a strong psychosocial impact and is often reported as a source of embarrassment, low self-esteem, social stigma, and barriers to interpersonal relationships. Malodour is a maker of bacterial colonization, and its role in HS is understudied. Objectives: The aim of this study is to assess the relationship between severity of malodourous discharge and quality-of-life impairment in patients with HS. Methods: This is a cross-sectional study of 51 patients recruited from the Women’s College Hospital and the York Dermatology Centre. Quality of life was assessed using both the Dermatology Life Quality Index (DLQI) and the Skindex-29 instruments. Results: Severity of odour significantly predicts the total Skindex score after controlling for disease severity as measured by the Hurley stage and Sartorius score ( R ~(2)= 0.39, F = 8.11, P R ~(2)= 0.17, F = 2.63, P = .064). There was no difference in mean DLQI scores for the low- vs high-odour groups, but patients with high odour had a greater quality of life impairment as measured by the Skindex tool ( t = ?4.19, df = 43, P < .0001, mean difference = ?18.87). Conclusion: Malodour is a common symptom that significantly impairs quality of life in patients with HS. The fact that this effect is captured in Skindex and not the DLQI may be attributed to the nonspecificity of the DLQI in terms of unique disease characteristics. It is important to address odour in the management of patients with HS.
机译：背景：HIDradenitisuptuativa（HS）患者的恶臭排放具有强烈的心理社会影响，经常被报告为尴尬，低自尊，社会耻辱和人际关系障碍的源泉。 Malodour是一种细菌定植制造商，其在HS中的作用被解读。目的：本研究的目的是评估HS患者的恶臭排放和寿命质量障碍之间的关系。方法：这是对妇女学院医院和约克皮肤科中心招募的51名患者的横截面研究。使用皮肤科生活质量指数（DLQI）和Skindex-29仪器进行评估生活质量。结果：气味的严重程度显着预测了通过Hurley阶段和Sartorius得分测量的疾病严重性（R〜（2）= 0.39，F = 8.11，Pr〜（2）= 0.17，f = 2.63， p = .064）。低于高气味群的平均dlqi分数没有差异，但高气味的患者具有更大的寿命损伤质量，如skindex工具（t = 4.19，df = 43，p <.0001 ，平均差异=？18.87）。结论：Malodour是一种常见的症状，可显着损害HS患者的生活质量。这种效果在Skindex中捕获而不是DLQI的事实可能归因于DLQI的非特征，就独特的疾病特征而言。解决HS患者管理中的气味很重要。

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