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首页> 外文期刊>Journal of drug targeting >Recent advances in electrospun for drug delivery purpose
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Recent advances in electrospun for drug delivery purpose

机译：驻防恒期近期进展用于药物递送目的

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摘要

Electrospun, an advanced technology, has been successfully employed for fibre production and offers many merits in novel drug delivery systems (DDSs). In recent years, electrospun has gained significant attention and attraction of the scientists in soaring numbers. This technology is superior to other technologies in fabricating the fibres which range from micrometers to manometers scale. The selection of appropriate polymers, electrospun processes and electrospun parameters play important roles in controlling the drug release while, treating serious illness. Besides, electrospraying process has similar characteristics to the electrospun and is presented briefly here. Further, in vivo and in vitro evaluations of the electrospun nanofibers are comprehensively discussed. In addition, the electrospun nanotechnology has been exploited to design drug release systems, investigate drug's pharmacokinetics and further develop DDS. The electrospun nanofibers improve bioactivity of various types of drugs including water-insoluble, soluble, anticancer and antibacterial drugs and genetic materials. In the end, the prospects and challenges in the process of designing drug-loaded electrospun nanofibers are discussed in detail.
机译：Electrome，一种先进的技术，已成功用于纤维生产，并在新型药物递送系统（DDS）中提供许多优点。近年来，Electromun在飙升的数字中获得了重大关注和吸引力。该技术优于制造纤维的其他技术，该技术范围从微米到压力测量秤。选择合适的聚合物，电纺过程和电纺场参数在控制药物释放时起着重要作用，同时治疗严重疾病。此外，电喷雾过程具有与Electromun的类似特性，并在此简要介绍。此外，综合地讨论了电纺纳米纤维的体内和体外评估。此外，电纺纳米技术已被利用以设计药物释放系统，调查药物的药代动力学并进一步发展DDS。 Electrom X型纳米纤维改善了各种类型药物的生物活性，包括水不溶性，可溶性，抗癌和抗菌药物和遗传物质。最后，详细讨论了设计载有吸毒的电纺纳米纤维的过程中的前景和挑战。

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