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A review of the molecular basis for reduced endometrial receptivity in uterine fibroids and polyps

机译:子宫肌瘤和息肉中子宫内膜接受性降低的分子基础综述

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摘要

The presence of fibroids and endometrial polyps is associated with reduced endometrial receptivity and subsequent fertility outcomes. The following review explores the molecular mechanisms behind reduced endometrial receptivity, with a focus upon homebox genes, basic transcription element binding proteins, transforming growth factor ?-3, and bone morphogenetic protein 2. A better understanding of these processes is essential for future targeted therapy.
机译:肌瘤和子宫内膜息肉的存在与减少的子宫内膜接受性和随后的生育结果有关。 以下审查探讨了子宫内膜接收性的分子机制,重点是家庭框基因,基本转录元件结合蛋白,转化生长因子Δ-3和骨形态发生蛋白2.更好地了解这些过程对于未来的目标治疗至关重要 。

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