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首页> 外文期刊>Journal of Experimental Botany >Upstream of gene expression: what is the role of microtubules in cold signalling?
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Upstream of gene expression: what is the role of microtubules in cold signalling?

机译:基因表达的上游:微管在冷信号中的作用是什么?

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摘要

Cold stress is a major abiotic stress, restricting plant growth and development. Therefore, gene expression in response to cold stress and during cold acclimation has been studied intensively, including the ICE-CBF-COR pathway, as well as the modulation of this cascade by secondary messengers, for instance mitogen-activated protein kinase (MAPK) cascades. In contrast, the early events of cold perception and cold adaption have received far less attention. This is partially due to the fact that cold is a physical signal, which requires the conceptual framework to be adjusted. In this review, we address the role of microtubules in cold sensing, and propose a model whereby microtubules, while not being part of signalling itself, act as modulators of cold sensitivity. The purpose of this model is to derive implications for future experiments that will help to provide a more complete understanding of cold adaptation.
机译:冷应激是一种重大的非生物应激,限制植物生长和发育。 因此,已经深入研究了响应于冷应激和冷置的基因表达,包括冰-CBF-COR途径,以及次要信使的这种级联的调节,例如丝裂剂活化的蛋白激酶(MAPK)级联 。 相比之下,冷感和寒冷适应的早期事件受到了不太关注。 这部分是由于冷的是物理信号,这需要调整概念框架。 在这篇综述中,我们解决了微管中的角色在寒冷传感中,并提出了一种微管的模型,而不是表示信号本身的一部分,充当冷灵敏度的调节剂。 该模型的目的是导出对未来实验的影响,这些实验将有助于提供更完全了解冷适应的理解。

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