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首页> 外文期刊>Journal of feline medicine and surgery >Field study assessing the performance of a patient-side blood test to determine neuter status in female cats based on detection of luteinising hormone
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Field study assessing the performance of a patient-side blood test to determine neuter status in female cats based on detection of luteinising hormone

机译：田间研究评估患者侧血液检测的性能，基于检测刻度激素的雌性猫确定中性状态

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Objectives The aim of this study was to assess the performance of a patient-side blood test in determining neuter status in female cats. Methods Residual blood samples from female cats of unknown neuter status that were admitted to four cat adoption centres in the UK were tested for luteinising hormone (LH) using the Witness LH test (Zoetis). A positive LH test result indicated that the cat was neutered. Cats were assessed for evidence of a surgical scar suggestive of prior neutering; if none was found, an exploratory laparotomy was performed to confirm neuter status. The LH test performance was assessed (sensitivity, specificity, negative and positive predictive value). Results Two hundred and thirty-six cats had both LH test and exploratory laparotomy data. The specificity of the test in detecting neutered cats was 100% (95% confidence interval 96.2-99.9) and the sensitivity was 69% (95% confidence interval 59.3-76.8). The prevalence of neutered cats in this sample was 49%. The positive and negative predictive values were 1 and 0.77, respectively. Conclusions and relevance The Witness LH test correctly detected all unneutered cats and thus there were no false-positive results that incorrectly indicated a cat was neutered. This study therefore suggests that positive LH test results avoid the need to perform surgery to confirm neuter status. This has significant welfare benefits for cats as it provides a lower risk, faster and less traumatic alternative to surgery and, in the shelter setting, it will have a positive impact on the cost, speed of assessment and time to rehoming of cats.
机译：目的本研究的目的是评估患者侧血液测试的表现，在雌性猫中确定中性状态。方法使用证人LH试验（Zoetis）对英国纳入四只猫采用中心的雌性猫的残留血液样本被录取到英国的四个猫收养中心。正LH测试结果表明猫是绝育的。评估猫的暗示前未绝育的外科瘢痕的证据;如果没有发现，则进行探索性剖面术以确认中性状态。评估LH测试性能（敏感性，特异性，消极和阳性预测值）。结果二百三十六只猫都有LH测试和探索性剖腹谱系数据。检测中性猫的测试的特异性为100％（95％置信区间96.2-99.9），敏感性为69％（95％置信区间59.3-76.8）。该样品中绝育猫的患病率为49％。正面和阴性预测值分别为1和0.77。结论和相关性证人LH检测正确检测到所有荒野的猫，因此没有错误的结果表明猫是绝育的。因此，本研究表明，正LH测试结果避免需要进行手术以确认中性状态。这对猫具有重要的福利益处，因为它提供了较低的风险，更快和更少创伤的手术，并且在避难所的环境中，它将对猫的成本，评估速度和时间的时间产生积极影响。

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