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首页> 外文期刊>Journal of forensic and legal medicine >Polymorphism of 15 short tandem repeat loci in Hui population of Ningxia Tongxin district
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Polymorphism of 15 short tandem repeat loci in Hui population of Ningxia Tongxin district

机译:宁夏通信区辉矿人群15次短串联重复基因岩多态性

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摘要

Abstract Objective To investigate the polymorphism of 15 STR loci in Hui population from Ningxia Tongxin district. Methods Identifiler Plus kit used to detect the allelic frequencies of 15 STR loci in 598 unrelated Tongxin Hui individuals, and the population genetics parameters were calculated by using statistic software. Results The results demonstrated that all loci were found to be no deviation from Hardy-Weinberg equilibrium (P?>?0.05), Heterozygosity (H) ranged from 0.637 to 0.868, matching probability ( Pm ) ranged from 0.034 to 0.213, power of discrimination (DP) ranged from 0.787 to 0.966, polymorphism information content (PIC) ranged from 0.560 to 0.850, power of exclusion (PE) ranged from 0.338 to 0.730. Conclusions The 15 STR loci are relatively abundant in polymorphic information and suitable for paternity testing and personal identification. Highlights ? Hui population of Ningxia Tongxin district accounts for 85.6% of the total county population, Tongxin is a region inhabited by the Hui people. ? Short tandem repeat (STR) has important significance in genetic mapping, gene diagnosis, disease screening, forensic individual identification, paternity testing and national research. ? This paper intends to investigate the polymorphism of 15 STR loci in Hui population from Ningxia Tongxin district, and provides basic data for the research and application of population genetics in this area.
机译:摘要目的探讨宁夏通信区慧氏人口15株洛卡的多态性。方法使用统计软件计算598个不相关的通心惠特中,用于检测598个不相关的通信汇位的等位基因频率的识别仪和套件。结果结果表明,发现所有基因座没有偏离Hardy-Weinberg平衡(P?> 0.05),杂合子(H)范围为0.637至0.868,匹配概率(PM)范围为0.034至0.213,歧视的力量(DP)范围为0.787至0.966,多态性信息含量(PIC)范围为0.560至0.850,排除功率(PE)范围为0.338至0.730。结论,15个STR基因座在多态信息中相对丰富,适用于亲属测试和个人识别。强调 ?宁夏惠人口占县总人口总人口的85.6%,桐鑫是由慧人居住的地区。还短串联重复(str)在遗传映射,基因诊断,疾病筛查,法医个体鉴定,亲子鉴定和国家研究方面具有重要意义。还本文旨在调查宁夏通信区汇普群的15个STR基因座的多态性,为该地区的群体遗传学的研究和应用提供了基本数据。

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