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首页> 外文期刊>Journal of glaucoma >The Influence of Corneal Biomechanical Properties on Intraocular Pressure Measurements Using a Rebound Self-tonometer
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The Influence of Corneal Biomechanical Properties on Intraocular Pressure Measurements Using a Rebound Self-tonometer

机译：角膜生物力学特性对使用回弹自体色调计的眼压测量的影响

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Purpose:The purpose of this study was to examine the effect of corneal biomechanical properties on intraocular pressure (IOP) measurements obtained using a rebound self-tonometer (Icare HOME) compared with Goldmann applanation tonometry (GAT).Methods:An observational study of 100 patients with glaucoma or ocular hypertension. All had a comprehensive ophthalmic examination and standard automated perimetry. IOP was assessed by GAT, Icare HOME and Ocular Response Analyzer, which was also used to assess corneal hysteresis (CH) and corneal resistance factor (CRF). Central corneal thickness (CCT) was recorded.Results:Mean (SD) IOP measurements were 14.3 +/- 3.9 and 11.7 +/- 4.7mmHg using GAT and Icare HOME, respectively. Average CCT, CRF, and CH were 534.5 +/- 37.3m, 9.0 +/- 1.7mmHg, and 9.4 +/- 1.5mmHg, respectively. The mean difference between Icare HOME and GAT was -2.66 +/- 3.13mmHg, with 95% limits of agreement of -8.80 to 3.48mmHg, however, there was evidence of proportional bias. There was negative correlation between IOP and CH [5.17mmHg higher Icare HOME IOP (P=0.041, R-2=0.029) and 7.23mmHg higher GAT IOP (P=0.008, R-2=0.080) for each 10mmHg lower CH], whereas thinner CCT was significantly associated with lower IOP (P0.001, R-2=0.14 for Icare HOME and P0.001, R-2=0.08 for GAT). In multivariable analysis, although CRF and CH remained associated with IOP measured using either GAT or Icare HOME, CCT was no longer significant.Conclusion:IOP measurements obtained using a self-tonometer, similar to GAT, were more influenced by overall corneal biomechanics than CCT.
机译：目的：本研究的目的是研究角膜生物力学性能对使用反弹自测（icare home）获得的眼压（IOP）测量的影响，与Goldmann Applanation Tonometry（GAT）相比。方法：100个观察研究青光眼或眼高血压患者。所有全部有综合性眼科检查和标准自动化周边。通过Gat，Icare Home和眼响应分析仪评估IOP，其还用于评估角膜滞后（CH）和角膜抵抗因子（CRF）。记录中央角膜厚度（CCT）。结果：平均值（SD）IOP测量分别使用GAT和ICare Home分别为14.3 +/- 3.9和11.7 +/- 4.7mmHg。平均CCT，CRF和CH分别为534.5 +/- 37.3m，9.0 +/- 1.7mmHg，9.4 +/- 1.5mmHg。 ICare Home和Gat之间的平均差异为-2.66 +/- 3.13mmg，但协议的95％限制为-8.80至3.48mmhg，但有一定比例偏见。 IOP和CH之间存在负相关性[5.17mmHg高级IP（P = 0.041，R-2 = 0.029）和7.23mmg较高的GAT IOP（P = 0.008，R-2 = 0.080），每个10mmHg下CH]，较薄的CCT与下游（P <0.001，R-2 = 0.14用于GAT）显着相关（P <0.001，R-2 0.001，R-2 = 0.08）。在多变量分析中，虽然CRF和CH与使用GAT或ICare Home测量的IOP相关，但CCT不再有显着性。结论：使用与GAT类似的自体眼压计获得的IOP测量比CCT更多地受到整体角膜生物力学的影响。

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