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The non-neoplastic kidney in tumor nephrectomy specimens: what can it show and what is important?

机译:肿瘤肾切除术标本中的非肿瘤性肾脏:它可以显示什么,什么重要?

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摘要

Surgical nephrectomy is a procedure that has been performed for nearly 100 years. In the presence of a normal contralateral kidney, such as in a renal transplant donor or child with Wilms tumor, it is a benign procedure without deleterious consequences on the remaining kidney. However, many adults and some children postnephrectomy will develop chronic kidney disease. The non-neoplastic kidney in tumor resections may harbor a large number of developmental and acquired diseases predictive of this outcome or that convey other medically significant information. Examination of the non-neoplastic kidney is a fertile opportunity to identify these unsuspected conditions that may ultimately dictate the subsequent clinical course and influence the medical care provided. This review discusses the consequences of unilateral and partial nephrectomy, and illustrates many conditions that may be encountered in the non-neoplastic cortex with a discussion of their clinical implications.
机译:手术肾切除术已经执行了将近100年。在正常对侧肾脏的情况下,例如在肾移植供体或患有Wilms肿瘤的儿童中,这是一种良性手术,对剩余的肾脏没有有害影响。但是,许多成年人和一些儿童肾切除术后会发展成慢性肾脏疾病。肿瘤切除中的非肿瘤性肾脏可能蕴藏着大量预示这种结果或传达其他医学上重要信息的发育性和获得性疾病。对非肿瘤性肾脏的检查是鉴别这些未曾预料到的状况的良机,这些状况可能最终决定随后的临床过程并影响所提供的医疗服务。这篇综述讨论了单侧和部分肾切除术的后果,并通过讨论其临床意义说明了非肿瘤皮层中可能遇到的许多情况。

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