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首页> 外文期刊>Journal of insect biotechnology and sericology >Identification and expression analysis of the replication factor C proteinin the silkworm, Bombyx mori
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Identification and expression analysis of the replication factor C proteinin the silkworm, Bombyx mori

机译:复制因子C蛋白的鉴定及表达分析蚕,Bombyx Mori

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摘要

The silkworm, Bombyx mori L. (Lepidoptera: Bombyci-dae), is an agriculturally crucial animal for silk production. Approximately 820 silkworm mutants have been deposited and categorized according to the color of the pupa, skin color, patterns of the larva, and color of the eggs (http://shigen.nig.ac.jp/silkwormbase/top.jsp). The phenotypes available for B. mori have been used in genetic studies. The recent focus in silkworm research has been on using the silkworm as an animal model in drug discovery and development instead of mice or other animals to confirm drug efficacy, studying the function of silkworm proteins, and utilizing it as an expression host for recombinant proteins. However, the cell cycle, including initiation of DNA replication, has not yet been investigated in B. mori. As an initial step toward understanding this process for this species, we attempted to identify factors involved in DNA replication.
机译:蚕,Bombyx Mori L.(Lepidoptera:Bombyci-Dae),是一种用于丝绸生产的农产品。 根据蛹,肤色,幼虫模式的颜色,以及鸡蛋的颜色(http://shigen.nig.ac.jp/silkwormbase/top.jsp),已经沉积和分类了大约820个蚕突变体。 可用于B. Mori的表型已被用于遗传研究。 近期在蚕的重点是使用蚕作为药物发现和开发中的动物模型而不是小鼠或其他动物,以确认蚕蛋白的功能,并利用其作为重组蛋白的表达宿主。 然而,尚未在B. Mori研究尚未研究细胞周期,包括DNA复制的开始。 作为理解该物种的初步步骤,我们试图识别DNA复制中涉及的因素。

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