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Tailored hydrogels for biosensor applications

机译：用于生物传感器应用的量身定制的水凝胶

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To date, hydrogels have gained attraction due to their inherent advantages such as wide selection of precursors and additives, low toxicity, easy shape control, and biological compatibility. Therefore, extensive studies are being conducted for their application in diverse fields. In this review, recent impressive studies on the use of tailored hydrogel materials for biosensor applications have been summarized. As the hydrogel precursors and the sensing mechanisms are wide and extensive, we have summarized chemical/biological sensors depending on the hydrogel precursors possessing biocompatible features. Hence, versatile biological/biochemical sensors using conventional hydrogels based on carbohydrates, polymers, DNA and peptides have been covered primarily. In addition, emerging conductive hydrogels possessing conducting additives such as graphene, conducting polymers, and nanocrystals have been introduced and their application in biosensors has been described extensively. Sensor operations are dependent on the changes in resistance and conductance, signal transduction through electrodes, sensor geometry, and interactions between sensing media and target analytes. As we primarily focused on the type of precursor materials and the sensor performance such as sensing mechanism, sensitivity, linear range, and selectivity was summarized and presented. A trend in the research fields of hydrogel-based elaborate sensors has also been briefly described. This article provides essential information for advanced research in related fields. (C) 2020 The Korean Society of Industrial and Engineering Chemistry. Published by Elsevier B.V. All rights reserved.
机译：迄今为止，水凝胶由于其固有的优点而获得吸引力，例如广泛的前体和添加剂，低毒性，易于形状控制和生物相容性。因此，正在为各种领域的应用进行广泛的研究。在本次审查中，总结了对使用定制的水凝胶材料进行生物传感器应用的令人印象深刻的研究。作为水凝胶前体和传感机制宽而广泛，我们已经概述了化学/生物传感器，这取决于具有生物相容性特征的水凝胶前体。因此，基于碳水化合物，聚合物，DNA和肽的使用常规水凝胶的多功能生物/生化传感器已被覆盖。另外，已经引入了具有导电添加剂如石墨烯，导电聚合物和纳米晶体的新出现的导电水凝胶，并且已经广泛描述了它们在生物传感器中的应用。传感器操作取决于通过电极，传感器几何形状和感测介质和目标分析物之间的相互作用的电阻和电导，信号转导的变化。随着我们主要专注于前体材料的类型和传感器性能，例如传感机构，灵敏度，线性范围和选择性，并呈现。还简要描述了水凝胶基精细传感器研究领域的趋势。本文为相关领域的高级研究提供了基本信息。 （c）2020朝鲜工业与工程化学学会。 elsevier b.v出版。保留所有权利。

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