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首页> 外文期刊>Journal of Materials Engineering and Performance >In Vitro Corrosion Behavior and Cytotoxicity of Polycaprolactone-Akermanite-Coated Friction-Welded Commercially Pure Ti/AZ31 for Orthopedic Applications
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In Vitro Corrosion Behavior and Cytotoxicity of Polycaprolactone-Akermanite-Coated Friction-Welded Commercially Pure Ti/AZ31 for Orthopedic Applications

机译：用于整形外科应用的多己内酯 - akermanite涂覆的摩擦焊接摩擦焊接摩擦焊接摩擦焊接的体外腐蚀行为和细胞毒性

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摘要

This study deals with the corrosion and bioactivity behavior of biodegradable friction-welded CP-Ti/AZ31 joints. The investigations were carried out on the bare, PCL-coated and PCL-akermanite (AKT)-coated joints immersed in simulated body fluid. The samples were subjected to polarization and impedance corrosion tests, weight loss and pH monitoring and cytotoxicity investigations as well as cell adhesion test. The results of corrosion tests and weight loss measurements indicated that whereas the bare alloy shows the highest corrosion rate through 7 days (15.945 mm/y), the PCL-AKT-coated sample presented significantly improved results, even when the soaking period was prolonged to 30 days. The PCL-AKT-coated sample also showed the best biocompatibility, as the cell viability was measured to be 97.52%. The Ca/P ratio was also measured to be about 1.64 for PCL-AKT-coated sample, indicating favorable osteogenic behavior. The results of alizarin red cell staining and absorption spectrum as well as alkaline phosphatase activity confirmed superior osteogenic behavior of the PCL-AKT-coated sample. It was found that the CP-Ti/AZ31 samples coated with PCL-AKT obtained suitable corrosion resistance and cellular response, thus presenting a good potential to be used in orthopedic applications.
机译：该研究涉及可生物降解的摩擦焊接CP-Ti / AZ31关节的腐蚀和生物活性行为。研究浸没在模拟体液中的裸露，PCL-涂层和PCL-Akermanite（AKT）涂覆的关节上进行。对样品进行极化和阻抗腐蚀试验，减肥和pH监测和细胞毒性研究以及细胞粘附试验。腐蚀试验和减肥测量结果表明，裸合金通过7天（15.945mm / Y）显示出最高的腐蚀速率，而PCL-AKT涂层样品呈现出显着改善的结果，即使浸泡期延长到30天。 PCL-AKT涂覆的样品还显示出最佳的生物相容性，因为测量细胞活力为97.52％。对于PCL-AKT涂覆的样品，也测量Ca / P比为约1.64，表明有利的骨质发生行为。茜素红细胞染色和吸收光谱的结果以及碱性磷酸酶活性证实了PCL-AKT涂覆的样品的优异成骨行为。发现涂有PCL-AKT的CP-TI / AZ31样品获得了合适的耐腐蚀性和细胞反应，从而呈现在整形外科应用中使用的良好电位。

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