Biocompatibility of Hydrogen-Diluted Amorphous Silicon Carbide Thin Films for Artificial Heart Valve Coating

Umesh Rizal; Bhabani S. Swain; N. Rameshbabu; Bibhu P. Swain

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Biocompatibility of Hydrogen-Diluted Amorphous Silicon Carbide Thin Films for Artificial Heart Valve Coating

机译：人造心阀涂层氢稀合非晶硅碳化硅薄膜的生物相容性

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Amorphous silicon carbide (a-SiC:H) thin films were synthesized using trichloromethylsilane by a hot wire chemical vapor deposition process. The deposited films were characterized by Fourier transform infrared spectroscopy (FTIR), Raman spectroscopy, x-ray diffraction and x-ray photoelectron spectroscopy to confirm its chemical bonding, structural network and composition of the a-SiC:H films. The optical microscopy images reveal that hydrogen dilution increased the surface roughness and pore density of a-SiC:H thin film. The Raman spectroscopy and FTIR spectra reveal chemical network consisting of Si-Si, C-C and Si-C bonds, respectively. The XRD spectroscopy and Raman spectroscopy indicate a-SiC:H still has short-range order. In addition, in vitro cytotoxicity test ensures the behavior of cell–semiconductor hybrid to monitor the proper coordination. The live–dead assays and MTT assay reveal an increase in green nucleus cell, and cell viability is greater than 88%, respectively, showing non-toxic nature of prepared a-SiC:H film. Moreover, the result indicated by direct contact assay, and cell prefers to adhere and proliferate on a-SiC:H thin films having a positive effect as artificial heart valve coating material.

机译：通过热线化学气相沉积工艺使用三氯甲基硅烷合成非晶碳化硅（A-SiC：H）薄膜。沉积的薄膜的特征在于傅里叶变换红外光谱（FTIR），拉曼光谱，X射线衍射和X射线光电子谱，以确认其化学键合，结构网络和A-SiC：H膜的组成。光学显微镜图像显示氢稀释增加了A-SiC：H薄膜的表面粗糙度和孔密度。拉曼光谱和FTIR光谱分别显示由Si-Si，C-C和Si-C键组成的化学网络。 XRD光谱和拉曼光谱表明A-SIC：H仍然有短距顺序。此外，体外细胞毒性检测确保了细胞半导体杂交机的行为，以监测适当的协调。活死测定和MTT测定揭示了绿色核细胞的增加，细胞活力分别大于88％，显示出制备的A-SiC：H膜的无毒性质。此外，通过直接接触测定的结果和细胞更喜欢粘附和增殖，并在具有正效应的A-SiC：H薄膜作为人造心脏瓣膜涂层材料。

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来源
《Journal of Materials Engineering and Performance》 |2018年第6期|共8页
作者
Umesh Rizal; Bhabani S. Swain; N. Rameshbabu; Bibhu P. Swain;
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作者单位

Nano Processing Laboratory Centre for Material Science and Nanotechnology Sikkim Manipal Institute of Technology;

School of Advanced Materials Engineering Kookmin University;

Department of Metallurgical and Materials Engineering National Institute of Technology;

Nano Processing Laboratory Centre for Material Science and Nanotechnology Sikkim Manipal Institute of Technology;

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原文格式 PDF
正文语种 eng
中图分类金属学与金属工艺;工程材料学;
关键词
apoptosis; a-SiC:H; cytotoxicity test; viability;

机译：细胞凋亡;a-sic：h;细胞毒性测试;可行性;

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1. Biocompatibility of Hydrogen-Diluted Amorphous Silicon Carbide Thin Films for Artificial Heart Valve Coating [J] . Umesh Rizal, Bhabani S. Swain, N. Rameshbabu, Journal of Materials Engineering and Performance . 2018,第6期

机译：人造心阀涂层氢稀合非晶硅碳化硅薄膜的生物相容性
2. Amorphous silicon carbide thin films (a-SiC:H) deposited by plasma-enhanced chemical vapor deposition as protective coatings for harsh environment applications [J] . W. Daves, A. Krauss, N. Behnel, Thin Solid Films . 2011,第18期

机译：通过等离子体增强化学气相沉积法沉积的非晶碳化硅薄膜（a-SiC：H）作为恶劣环境应用中的保护涂层
3. Nonstoichiometric amorphous silicon carbide films as promising antireflection and protective coatings for germanium in IR spectral range [J] . Lukianov A. N., Klyui N. I., Sha Bo, Optical Materials . 2019,第FEBa期

机译：非化学计量的非晶碳化硅薄膜可作为锗在红外光谱范围内的抗反射和保护涂层
4. Controlled Growth of Nanocrystalline Silicon within Amorphous Silicon Carbide Thin Films [C] . Arindam Kole, Partha Chaudhuri DAE Solid State Physics Symposium . 2014

机译：无定形碳化硅薄膜内的纳米晶硅的控制生长
5. Characterization of amorphous silicon carbide and silicon carbonitride thin films synthesized by polymer-source chemical vapor deposition. Mechanical structural and metal-interface properties [D] . Awad, Yousef 2006

机译：通过聚合物源化学气相沉积合成的非晶碳化硅和碳氮化硅薄膜的表征。机械结构和金属界面性能
6. Enhanced Photoluminescence of Hydrogenated Amorphous Silicon Carbide Thin Films by Means of a Fast Thermal Annealing Process [O] . Israel Vivaldo, Roberto C. Ambrosio, Roberto López, 2020

机译：通过快速热退火工艺增强氢化非晶碳化硅薄膜的光致发光
7. HYDROGENATED AMORPHOUS SILICON CARBIDE FILMS AS PERSPECTIVE TRIBOLOGICAL COATINGS AND SEMICONDUCTOR LAYERS [O] . 1062

机译：氢化非晶碳化硅薄膜作为透视摩擦涂层和半导体层

Biocompatibility of Hydrogen-Diluted Amorphous Silicon Carbide Thin Films for Artificial Heart Valve Coating

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