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首页> 外文期刊>Journal of Neuroimmunology: Official Bulletin of the Research Committee on Neuroimmunology of the World Federation of Neurology >Risk factors of attacks in neuromyelitis optica spectrum disorders
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Risk factors of attacks in neuromyelitis optica spectrum disorders

机译：神经肌炎OPTICA谱紊乱攻击的危险因素

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摘要

Predisposing factors before the onset of neuromyelitis optica spectrum disorders (NMOSD) have not been systematically evaluated by now. We investigated the detailed pre-onset history in consecutive NMOSD patients. Thirteen of the enrolled 53 NMOSD patients (24.5%) had accompanying autoimmune diseases, such as Sjogren's syndrome. History of malignancy was seen in 8 of the 53 patients (15.1%). Recent history of non-neurological clinical episodes, such as systemic allergic reaction, systemic infection, surgical operation, or traumatic injury, was seen in 23 of the 53 patients (43.4%). NMOSD patients are likely to have pre-onset history of other autoimmune diseases, malignancy, or recent non-neurological systemic conditions, which may predispose or trigger the onset of NMOSD.
机译：目前尚未系统地评估了神经肌炎Optica谱紊乱（NMOSD）前的易感性因素。 我们调查了连续的NMOSD患者的详细前期历史。 13名注册的53名患者（24.5％）伴随着自身免疫性疾病，如Sjogren的综合症。 53名患者中有8例（15.1％）见到恶性肿瘤病史。 近期非神经临床发作的历史，如系统性过敏反应，全身感染，手术操作或创伤损伤，在53名患者中有23例（43.4％）。 NMOSD患者可能具有其他自身免疫性疾病的预发病史，恶性肿瘤或最近的非神经系统条件，这可能易于影响或引发NMOSD的发作。

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