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首页> 外文期刊>Journal of paediatrics and child health >Barriers to the implementation of isoniazid preventive therapy for tuberculosis in children in endemic settings: A review
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Barriers to the implementation of isoniazid preventive therapy for tuberculosis in children in endemic settings: A review

机译：在流动环境中实施儿童肺结核患者的异喹啉预防治疗的障碍：综述

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摘要

Abstract Isoniazid preventive therapy is one of the key interventions in reducing the risk of active disease among children exposed to tuberculosis. However, initiation and maintenance of this treatment is poor in many areas. This review summarises the existing literature on barriers to implementation of isoniazid preventive therapy for tuberculosis in children in endemic settings. MEDLINE, EMBASE and CINAHL databases were used to search for primary research studies published between 1998 and 2018, specifically mentioning isoniazid preventive therapy, tuberculosis and children. Barriers identified in most study settings included absence of parental risk perception, health‐care worker knowledge gaps and treatment access. Focusing on patient‐centred care, enhancing community and health‐care worker education and securing stable medication supply to effectively deliver this therapy is crucial in order to reduce childhood morbidity and mortality from tuberculosis.
机译：摘要异烟肼预防疗法是降低暴露于结核病的儿童活跃病风险的关键干预措施之一。 然而，这种治疗的启动和维护在许多领域都很差。 本综述总结了现有的文献，以了解异烟肼预防治疗细菌病患者在流动环境中的结核病。 MEDLINE，EMBASE和CINAHL数据库用于搜索1998年至2018年间发布的初级研究研究，特别是ISoniazid预防治疗，结核病和儿童。 大多数研究环境中确定的障碍包括孕妇风险感知，保健工作者知识差距和治疗访问。 重点关注患者中心护理，增强社区和保健工作者教育，并确保稳定的药物供应，以有效地递送这一疗法是至关重要的，以减少小结核病的儿童发病率和死亡率至关重要。

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