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首页> 外文期刊>Journal of paediatrics and child health >Lessons learned from a hospital‐wide review of blood stream infections for paediatric central line‐associated blood stream infection prevention
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Lessons learned from a hospital‐wide review of blood stream infections for paediatric central line‐associated blood stream infection prevention

机译：从医院血流感染的医院审查中学到的经验教训，用于儿科中央线相关血流感染预防

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Aim Bacteraemia episodes were assessed to calculate a hospital‐wide central line‐associated blood stream infection (CLABSI) rate per 1000 catheter‐days. Secondary objectives were to describe risk factors, microbiology and outcomes of children with CLABSI. Methods A retrospective study was conducted at an Australian tertiary paediatric hospital in children 18?years who had blood culture sampling during the 2‐year period, 2014–2015. All blood culture results were extracted from the hospital's laboratory information system. National Healthcare Safety Network Centres for Disease Control and Prevention definitions for bacteraemia classification were used. Central venous access device (CVAD) insertion and removal dates were obtained from a surgical electronic database and anaesthetic records and then manually validated. Results Of 11?774 processed blood culture bottles, 207 episodes of blood stream infection were observed. Eighty‐five (41%) episodes were community‐acquired bacteraemia (CA‐B) and 122 (59%) health care‐associated bacteraemia (HA‐B), of which 73 (35%) were CLABSI. The hospital‐wide CLABSI rate was 0.62 per 1000 catheter‐days (95% confidence interval: 0.49–0.77). Conditions associated with CLABSI were malignancy ( n =?45, 62%) and gastrointestinal failure ( n = 6, 8%). Thirty‐three (45%) CLABSI episodes developed in an outpatient setting. Conclusions HA‐B has a significant impact on child health, exceeding the number of CA‐B at our hospital. Children with CVADs are vulnerable in both the inpatient and outpatient settings. Collecting robust data for a hospital‐wide CLABSI rate is important to understand the full spectrum of paediatric CLABSI. The value of validating data using both electronic and manual methods is demonstrated.
机译：评估AIM菌血症发作，以计算每1000个导管天的医院宽的中央线相关血液流感染（CLABSI）率。次要目标是描述具有Clabsi的儿童的风险因素，微生物学和结果。方法在澳大利亚儿童的澳大利亚特权医院进行回顾性研究，在2014 - 2015年2年期间有血液文化抽样的血液文化抽样。所有血液培养结果均取自医院的实验室信息系统。使用国家医疗保健安全网络疾病控制和预防菌类分类定义。从外科电子数据库和麻醉记录中获得中心静脉接入装置（CVAD）插入和拆卸日期，然后手动验证。结果11？774种加工血液培养瓶，207次血流感染发作。八十五次（41％）发作是社区获得的菌株（CA-B）和122（59％）卫生保健相关的菌血症（HA-B），其中73（35％）是Clabsi。每1000个导管天数为0.62级的医院范围内（95％置信区间：0.49-0.77）。与Clabsi相关的病症是恶性肿瘤（n = 45,62％）和胃肠道失败（n = 6,8％）。在门诊设置中开发了三十三（45％）Clabsi剧集。结论HA-B对儿童健康产生重大影响，超过了我们医院的CA-B数量。具有CVADS的儿童在住院患者和门诊环境中都很脆弱。为医院范围的Clabsi率收集强大的数据对于了解全谱的儿科蛤蜊是重要的。使用电子和手动方法验证数据的值。

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