...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of Oral and Maxillofacial Surgery >Osseointegration of dental implants in rabbit bone with low mineral density.
【24h】

Osseointegration of dental implants in rabbit bone with low mineral density.

机译：兔骨中牙科植入物低矿物密度的骨整合。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

PURPOSE: The purposes of this study were to establish an experimental animal model with bone of low mineral density, and to then investigate the reaction of the bone-implant interface in these experimental animals. MATERIALS AND METHODS: To prepare the experimental model, rabbits were ovariectomized and fed a 0.15% low-calcium diet. The bone mineral density (BMD) of the tibia was periodically measured by dual-energy X-ray absorptiometry. Approximately 1 month after the introduction of the low-calcium diet, when BMD had decreased to about 12% less than that of control rabbits, a titanium implant (TI) was inserted into the tibia of each rabbit. At 2, 4, 8, and 12 weeks after the insertion of the TI, the rabbits were killed, and the reaction of the bone tissue surrounding the TI was examined both histologically and radiographically. RESULTS: The combined ovariectomy and low-calcium diet produced rabbits having bone with low mineral density, and the histologic features of the tibia in these rabbits were consistent with those in human osteoporotic bone. In control rabbits, new bone formation surrounding the TI was evident 2 weeks after its insertion, and the TI surface was almost completely covered with new bone after 8 weeks. In contrast, new bone formation in the experimental rabbits was delayed, but considerable direct bone contact with the TI was observed after 12 weeks. CONCLUSION: These results suggest that osteoporotic bone may affect the healing period of bone tissue after the insertion of dental implants, but that osseointegration of dental implants may be obtained even in osteoporotic bone.
机译：目的：本研究的目的是建立具有低矿物质密度的骨骼的实验动物模型，然后研究这些实验动物中的骨植入界面的反应。材料和方法：制备实验模型，兔卵巢切除并喂养0.15％低钙饮食。通过双能X射线吸收测定法定期测量胫骨的骨矿物密度（BMD）。在引入低钙饮食后大约1个月，当BMD减少到比对照兔的约12％少12％时，将钛植入物（Ti）插入每只兔子的胫骨中。在插入Ti之后的2,4,8和12周，兔子被杀死，并且在组织学和射线照相上检查Ti周围的骨组织的反应。结果：卵巢切除术和低钙饮食产生的兔子含有低矿物质密度的兔，这些兔子中胫骨的组织学特征与人骨质疏松骨骼中的那些一致。在对照兔子中，插入后2周围绕Ti的新骨形成，并且在8周后，Ti表面几乎完全覆盖着新骨。相比之下，在实验兔中的新骨形成被延迟，但在12周后观察到与Ti相当大的直接骨接触。结论：这些结果表明，在插入牙科植入物后，骨质疏松骨可能影响骨组织的愈合周期，但即使在骨质疏松骨中也可以获得牙科植入物的骨整合。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号