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首页> 外文期刊>Journal of neurology >Iodinated contrast agents in patients with myasthenia gravis: a retrospective cohort study
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Iodinated contrast agents in patients with myasthenia gravis: a retrospective cohort study

机译：患有肌肌肌无力患者的造影剂：回顾性队列研究

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Currently, it has not been satisfactorily established, whether modern low-osmolality iodinated contrast agents (ICAs) used in computed tomography (CT) studies are a risk factor for exacerbation of myasthenic symptoms. The rate of acute adverse events as well as delayed clinical worsening up to 30 days were analyzed in 73 patients with confirmed myasthenia gravis (MG) who underwent contrast-enhanced CT studies and compared to 52 patients who underwent unenhanced CT studies. One acute adverse event was documented. 12.3% of MG patients experienced a delayed exacerbation of symptoms after ICA administration. The rate of delayed severe exacerbation was higher in the contrast-enhanced group. Alternative causes for the exacerbation of MG-related symptoms were more likely than ICA administration in all cases. ICA administration for CT studies in MG patients should not be withheld if indicated, but patients particularly those with concomitant acute diseases should be carefully monitored for exacerbation of symptoms.
机译：目前，它尚未令人满意地建立，无论是否在计算机断层扫描（CT）研究中使用的现代低渗透压膜造影剂（ICA）是一种恶化染发剂症状的危险因素。在73名患有对比增强的CT研究的肌球血症（MG）的73名患者中分析了急性不良事件以及延迟临床恶化的临床恶化的速度，并与52名接受过型CT研究的患者进行了比较。记录了一个急性不良事件。 12.3％的MG患者在ICA管理后经历了症状的延迟恶化。对比度增强组延迟严重加剧的速率较高。在所有情况下，与ICA给药更可能加剧MG相关症状的替代原因。 CT患者CT研究的ICA管理如果指出，则不应扣留，但患者应仔细监测患者，尤其应仔细监测伴随症状的急性疾病。

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