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首页> 外文期刊>Journal of neurology >Posterior reversible encephalopathy syndrome
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Posterior reversible encephalopathy syndrome

机译:后逆转脑病综合征

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摘要

The posterior reversible encephalopathy syndrome (PRES) is a neurological disorder of (sub) acute onset characterized by varied neurological symptoms, which may include headache, impaired visual acuity or visual field deficits, disorders of consciousness, confusion, seizures, and focal neurological deficits. In a majority of patients the clinical presentation includes elevated arterial blood pressure up to hypertensive emergencies. Neuroimaging, in particular magnetic resonance imaging, frequently shows a distinctive parieto-occipital pattern with a symmetric distribution of changes reflecting vasogenic edema. PRES frequently develops in the context of cytotoxic medication, (pre) eclampsia, sepsis, renal disease or autoimmune disorders. The treatment is symptomatic and is determined by the underlying condition. The overall prognosis is favorable, since clinical symptoms as well as imaging lesions are reversible in most patients. However, neurological sequelae including long-term epilepsy may persist in individual cases.
机译:后验脑病综合征(Pres)是一种神经系统障碍(亚)急性发作,其特征是多种神经症状,其可包括头痛,视力受损或视野缺陷,意识障碍,混乱,癫痫发作和局灶性神经缺陷。在大多数患者中,临床介绍包括高血压紧急情况的动脉血压升高。神经化,特别是磁共振成像,经常显示出独特的平原枕部模式,其对称分布反射血管内水肿的变化。经常在细胞毒性药物的背景下发育(前)葛兰素,脓毒症,肾病或自身免疫疾病。治疗是症状的,由潜在条件决定。总体预后是有利的,因为在大多数患者中,临床症状以及成像病变是可逆的。然而,包括长期癫痫的神经系统后遗症可能持续在个体情况下。

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