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首页> 外文期刊>Journal of patient safety >Critical drug-drug interactions for use in electronic health records systems with computerized physician order entry: review of leading approaches.
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Critical drug-drug interactions for use in electronic health records systems with computerized physician order entry: review of leading approaches.

机译：用于电子健康记录系统的临界药物 - 药物互动，具有计算机化医师秩序条目：审查领先方法。

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Medications represent the most common intervention in health care, despite their benefits; they also lead to an estimated 1.5 million adverse drug events and tens of thousands of hospital admissions each year. Although some are not preventable given what is known today, many types are, and one key cause which is preventable is drug-drug interactions (DDIs). Most electronic health record systems include programs that can check and prevent these types of interactions as a routine part of medication ordering. Studies suggest that these systems as implemented often do not effectively screen for these DDIs. A major reason for this deficiency is the lack of any national standard for the critical DDIs that should be routinely operationlized in these complex systems. We review the leading critical DDI lists from multiple sources including several leading health systems, a leading commercial content provider, the Leapfrog CPOE Testing Standard, and the new Office of the National Coordinator (ONC) DDI List. Implementation of strong DDI checking is one of the important steps in terms of realizing the benefits of electronic prescribing with respect to safety. Hopefully, the ONC list will make it easier for organizations to ensure they are including the most important interactions, and the Leapfrog List may help these organizations develop an operational DDI list that can be practically implemented. In addition, this review has identified 7 common DDIs that can be the starting point for all organizations in this area of medication safety.
机译：尽管有益于健康，但药物可能代表医疗保健最常见的干预;他们还导致估计有150万不良药物事件和每年成千上万的医院入院。虽然在今天所知的情况下，一些不可预防的一些类型，但是可以预防的一个关键原因是药物 - 药物相互作用（DDI）。大多数电子健康记录系统包括可以检查和防止这些类型交互的程序作为药物排序的常规部分。研究表明，这些系统通常不会有效地筛选这些DDI。这种缺陷的主要原因是缺乏任何国家标准的临界DDI，应该在这些复杂的系统中经常运作。我们审查了来自多个来源的主要关键DDI列表，包括若干领先的卫生系统，领先的商业内容提供商，Leapfrog CPOE测试标准和国家协调员（ONC）DDI列表的新办事处。强大的DDI检查的实施是实现对安全的电子处方的好处的重要步骤之一。希望ONC列表将使组织更容易以确保它们包括最重要的交互，而LeapFrog列表可以帮助这些组织开发可以实际实现的操作DDI列表。此外，本综述已确定7个常见DDI，可以成为该领域的所有组织的起点。

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