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首页> 外文期刊>American journal of clinical dermatology >Adverse effects of biological agents in the treatment of psoriasis.
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Adverse effects of biological agents in the treatment of psoriasis.

机译:生物制剂在治疗牛皮癣中的不良作用。

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摘要

Tumour necrosis factor (TNF) antagonists are generally well tolerated, but carry the risk of side effects. In patients with psoriasis, the potential risks with anti-TNF agents may be overestimated because the most commonly reported adverse events are based on studies in patients with rheumatoid arthritis or inflammatory bowel disease. Whereas patients with psoriasis typically receive monotherapy, these patients are treated with biological-based combination therapies. Furthermore, patients with psoriasis have distinctive and different comorbidities, which could play a role in the development of different adverse events. However, the potential risks of the use of biological agents should always be taken into consideration.
机译:肿瘤坏死因子(TNF)拮抗剂通常耐受性良好,但有产生副作用的风险。在牛皮癣患者中,抗TNF药物的潜在风险可能被高估了,因为最常见的不良事件是基于类风湿性关节炎或炎症性肠病患者的研究。牛皮癣患者通常接受单一疗法,而这些患者则采用基于生物学的联合疗法进行治疗。此外,牛皮癣患者具有独特和不同的合并症,这可能在不同不良事件的发生中起作用。但是,应始终考虑使用生物制剂的潜在风险。

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