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首页> 外文期刊>Journal of Parasitology >ANTHELMINTIC DRUGS: THEIR EFFICACY AND COST-EFFECTIVENESS IN DIFFERENT PARITY CATTLE
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ANTHELMINTIC DRUGS: THEIR EFFICACY AND COST-EFFECTIVENESS IN DIFFERENT PARITY CATTLE

机译：Anthelmintic药物：不同平等牛的疗效和成本效益

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Gastrointestinal nematodes are responsible for economic losses in bovines and are characterized by reduced milk production, decreased working efficiency, and even death. In our study, the effect of different anthelmintic treatments on nematode control in different parity cattle (Friesian crossbreds) at calving and their effect on milk yield were evaluated. The economics of anthelmintics and farm benefits in terms of increased milk production after deworming was also calculated. We screened cattle of first and second parity for nematodes. Animals were randomly selected in each group. In first parity animals, there were 23 positive cattle found, which were divided into 3 different groups, while in second parity animals there were 20 positive cattle which were also divided into 3 groups. For treatment of gastrointestinal nematodes, we used albendazole (velbazine) at 10 mg/kg body weight and levamisole (Nilverm (R)) at 7.5 mg/kg. In this study, both drugs were found effective in controlling nematode infections in cattle. Percentage reduction of eggs per gram (EPG) by albendazole was 48.20, 85.34, and 93.90% and 51.54, 81.43, 91.74% on day 7, 14, and 21 in first and second parity animals, respectively. Percentage reduction of EPG by levamisole was 44.45, 76.92, and 88.03% and 46.60, 73.78, 85.43% on day 7, 14, and 21 in first and second parity animals, respectively. The average increase in milk production in albendazole-treated groups was 0.39 and 0.92 L per day while increases in levamisole treated groups were 0.27 and 0.55 L per day in first and second parity cattle, respectively. After treatment, albendazole increased the milk fat by 0.07 and 0.1% while levamisole decreased by 0.02 and 0.05% in first and second parity cattle, respectively. It is concluded that anthelmintic treatments of recently calved cattle have a significant effect on milk production due to the nematode control. Milk production increased significantly in second parity cattle following anthelmintic treatment as compared to first parity animals. Levamisole had a negative effect on fat concentration in cattle while albendazole-treated cattle showed a positive effect. Albendazole has been found more efficient in reducing EPG of helminths in both parity animals as compared to levamisole-treated animals while the cost-benefit ratio of levamisole was greater than albendazole.
机译：胃肠道线虫对牛的经济损失负责，其特点是牛奶生产减少，工作效率降低，甚至死亡。在我们的研究中，评估了在产犊时不同奇偶牛（Friesian杂交）在不同奇偶牛（Friesian杂交）对线虫控制的影响及其对牛奶产量的影响。还计算了在驱虫后增加牛奶产量增加的Anthelmintics和农业益处的经济学。我们筛选了Nematodes的第一和第二个平等的牛。在每组中随机选择动物。在第一阶段性动物中，发现了23个阳性牛，分为3种不同的群体，而在第二个平等动物中，有20个阳性牛，也分为3组。为了治疗胃肠道线虫，我们使用在7.5mg / kg的10mg / kg体重（nilverm（r））下的阿仑唑（velbazine）。在这项研究中，发现两种药物都有效地控制牛中的线虫感染。 Albendazole每克（EPG）的卵数百分比分别为48.20,85.34和93.90％和51.54,81.43,91.74％，分别在第一和第二级别动物中的第7,14和21天。左旋氨酸百分比的百分比为44.45,76.92和88.03％和46.03％，73.78,85.43％，第7,14,21和21天，在第一个和第二个平等动物中。每天牛奶生产中牛奶产量的平均增加为0.39和0.92L，而左旋吲哚治疗组的增加分别为每天0.27和0.55L，分别为第一和第二阶段牛。治疗后，阿苯唑增加了0.07％和0.1％，而左旋甲醚分别在第一和第二次奇级牛中减少0.02％和0.05％。得出结论是，由于线虫控制，最近重校牛的近距离治疗对牛奶产量的显着影响。与第一阶段动物相比，牛奶产量在血液治疗后的第二个平等牛伴有显着增加。左胺对牛的脂肪浓度产生负面影响，而阿美唑治疗的牛表现出积极效果。与左旋吲哚治疗的动物相比，在两次平等动物中减少了嗜睡剂的胃症患者的EPG，同时左旋吲哚的成本效益比大于苯磺唑。

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