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Mimics of cutaneous lymphoma: report of the 2011 society for hematopathology/european association for haematopathology workshop.

机译:皮肤淋巴瘤的模拟物:2011年血液病理学学会/欧洲血液病理学协会研讨会的报告。

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摘要

The Society for Hematopathology and European Association for Haematopathology workshop, from October 27 to 29, 2011, in Los Angeles, CA, exhibited many exemplary skin biopsy specimens with interesting inflammatory changes mimicking features of cutaneous lymphoma. This article reviews features observed in cutaneous lymphoid hyperplasia, cutaneous drug reactions, lupus-associated panniculitis, pityriasis lichenoides, hypereosinophilic syndrome, histiocytic necrotizing lymphadenitis, traumatic ulcerative granuloma with stromal eosinophils, and pigmented purpuric dermatosis, as well as a brief review of the pertinent literature and discussion of submitted conference cases. For the pathologist, it is important to be aware of diagnostic pitfalls as well as the limitations of ancillary testing (eg, clonality studies). Finally, correlation with total clinical information, good communication with clinical colleagues, close clinical follow-up with rebiopsy, and prudent use of laboratory studies are vital and will likely offer the best path toward a correct diagnosis.
机译:血液病理学学会和欧洲血液病理学协会研讨会于2011年10月27日至29日在加利福尼亚州洛杉矶举行,展出了许多示例性皮肤活检标本,这些标本具有类似于皮肤淋巴瘤特征的有趣的炎症变化。本文回顾了在皮肤淋巴样增生,皮肤药物反应,狼疮相关性脂膜炎,糠疹糠疹,嗜酸性粒细胞增多症,组织细胞性坏死性淋巴结炎,外伤性溃疡性肉芽肿伴间质性嗜酸性粒细胞和色素性紫癜性皮肤病的研究中所观察到的特征,并对此进行了简要综述文献和提交会议案例的讨论。对于病理学家而言,重要的是要意识到诊断的缺陷以及辅助测试的局限性(例如,克隆性研究)。最后,与全部临床信息的相关性,与临床同事的良好沟通,对活检进行密切的临床随访以及对实验室研究的谨慎使用至关重要,这很可能为正确诊断提供最佳途径。

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