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首页> 外文期刊>Journal of stroke and cerebrovascular diseases: The official journal of National Stroke Association >Carotid Webs in Cryptogenic Ischemic Strokes: A Matched Case-Control Study
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Carotid Webs in Cryptogenic Ischemic Strokes: A Matched Case-Control Study

机译：阴暗缺血卒中中的颈动脉网：一个匹配的病例对照研究

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摘要

Background: Young individuals with symptomatic carotid webs may be predisposed to ischemic strokes. However, evidence remains scarce. This investigation reports the frequency of carotid webs among patients with cryptogenic strokes compared to a control group. Methods: Consecutive cryptogenic ischemic strokes and trauma patients were identified. Additional inclusion criteria required age 18-60 years and availability of head/neck computed tomography (CT) angiography. CT angiogram (CTA) neck images were evaluated independently by 2 fellowshiptrained specialists. A carotid web was defined by a shelf-like, linear filling defect in the posterior internal carotid artery bulb. Results: Of 1877 patients presenting with ischemic strokes in 2015-2017, 165 were diagnosed with cryptogenic strokes, 51 of whom met the inclusion criteria of age and CTA availability. Fifty one trauma cases were matched for age and sex. After imaging analysis, 13 carotid webs (25%) were identified in the 51 cryptogenic stroke group versus 0 (0%; P < .001) in trauma subjects. Thirty-nine of the 51 cryptogenic ischemic stroke patients were found with carotid anterior distribution infarcts, of which 9 (23%) were found with ipsilateral carotid webs. There were more proximal large vessel occlusions in the cryptogenic patients with carotid webs, compared to those without (P = .04). All carotid webs led to less than 30% degree of stenosis. Conclusions: Carotid webs were found at a significantly higher frequency in patients with cryptogenic ischemic strokes compared to controls, indicating a potentially thrombogenic nature of these lesions in young patients. Additionally, intracranial large vessel occlusions were more common in patients with symptomatic carotid webs, presenting with ipsilateral strokes.
机译：背景：患有症状颈动脉腹肌的年轻个体可能被倾向于缺血性卒中。但是，证据仍然稀缺。与对照组相比，该研究报告了阴性脑卒中患者颈动脉腹带的频率。方法：鉴定了连续的加密缺血性脑卒中和创伤患者。额外的含有标准需要年龄18-60岁及头部/颈部计算机断层扫描（CT）血管造影的可用性。 CT血管造影（CTA）颈部图像独立于2名来自兄弟身份的专家进行评估。颈动脉纤维网由后腔内颈动脉灯泡中的搁板状线性填充缺陷定义。结果：2015 - 2017年缺血性卒中的1877例患者患有165例，诊断出患有密码术中风，其中51人符合纳入年龄和CTA可用性标准。年龄和性别匹配五十个一个创伤病例。在成像分析后，在创伤受试者中，在51个密码脑卒中组中鉴定了13个颈动脉纤维网（25％）。在颈动脉内分布梗塞中发现了51例51个密集型缺血性脑卒中患者，其中发现9（23％），用同侧颈动脉纤维网发现。与没有（P = 0.04）的颈动脉腹带有更多的颈动脉患者在阴道型患者中有更多的近端大血管闭塞。所有颈动脉幅导致狭窄程度不到30％。结论：与对照组相比，阴性缺血性卒中患者的患者发现颈动脉纤维绿网，表明年轻患者中这些病变的潜在血栓形成性质。另外，颅内大血管闭塞在患有症状颈动脉纤维腹腹肌中更常见，呈现同侧笔触。

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