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首页> 外文期刊>Journal of stroke and cerebrovascular diseases: The official journal of National Stroke Association >Predicting the Risk of Stroke in Chinese Internal Carotid Artery Stenosis Patients Underwent Carotid Artery Stenting: Validation and Improvement of Siena Carotid Artery Stenting Risk Score
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Predicting the Risk of Stroke in Chinese Internal Carotid Artery Stenosis Patients Underwent Carotid Artery Stenting: Validation and Improvement of Siena Carotid Artery Stenting Risk Score

机译：预测中国内部颈动脉狭窄患者中风的风险术后颈动脉支架：验证和改进锡耶纳颈动脉支架风险得分

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Background: Siena carotid artery stenting (CAS) risk score is developed based on Chinese internal carotid artery (ICA) stenosis patients recruited in Italy, whether it is equally applicable in Chinese remains unknown. We aimed to investigate Siena CAS risk score value for predicting stroke risk in ICA stenosis patients underwent CAS and explore additional factors for improving accuracy of scoring system. Methods: Totally 401 patients with ICA stenosis who underwent CAS were enrolled. The clinical data (including patient characteristics, lesion features, and procedure-related features) were collected and the Siena CAS score was calculated. Stroke incidence with 30 days was documented. Results: The incidence of stroke was 4.5%, and the Siena CAS score in stroke patients was higher compared with nonstroke patients, further receiver operating characteristic (ROC) curve illustrated that Siena CAS score was acceptable at predicting stroke risk with area under curve (AUC) of .743 (95%CI: .638-.848). Multivariate logistic regression model revealed that Siena CAS score and current fasting-blood glucose (FBG) greater than 7.1 mmol/l independently predicted higher stroke risk; followed ROC curve disclosed that Siena CAS score combined with current FBG greater than 7.1 mmo1/1 was of good value in predicting stroke risk (AUC: .770 (95%CI: .677-.863)), which was numerically increased compared with Siena CAS score alone. Conclusions: Siena CAS risk scoring system exhibits to be a useful tool to predict stroke risk, and the combination of Siena CAS score and current increased FBG might be a more accurate stratification for stroke risk in Chinese ICA stenosis patients after CAS.
机译：背景：锡耶纳颈动脉支架（CAS）风险评分是基于中国内部颈动脉（ICA）令人兴奋的患者在意大利招聘的患者开发，无论是在中国人是否同样适用的遗骸。我们的旨在调查锡耶纳CAS风险评分值，以预测ICA狭窄患者患者的中风风险，并探索提高评分系统准确性的额外因素。方法：共有401例患有CAS的ICA狭窄患者。收集了临床数据（包括患者特征，病变特征和程序相关的特征），并计算Siena CAS得分。记录了30天的中风发病率。结果：中风发病率为4.5％，与卒中患者的锡耶纳CAS评分比非行程患者相比，进一步的接收器操作特征（ROC）曲线说明了Siena CAS得分在预测曲线下的区域（AUC） ）.743（95％CI：.638-.848）。多变量逻辑回归模型显示，锡耶纳CAS得分和电流禁食血糖（FBG）大于7.1mmol / L独立预测的卒中风险; ROC曲线公开说，锡耶纳CAS得分与当前FBG相结合，大于7.1mmo1 / 1的预测中风风险具有良好的价值（AUC：.770（95％CI：.677-.863））与其数值增加锡耶纳斯卡级得分单独。结论：Siena CAS风险评分系统展示成为预测中风风险的有用工具，锡耶纳CAS评分和当前的联合的FBG可能是CAS后中国ICA狭窄患者中风风险的更准确分层。

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