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首页> 外文期刊>Journal of stroke and cerebrovascular diseases: The official journal of National Stroke Association >Contrast-Induced Nephropathy in Ischemic Stroke Patients Undergoing Computed Tomography Angiography: CINISter Study
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Contrast-Induced Nephropathy in Ischemic Stroke Patients Undergoing Computed Tomography Angiography: CINISter Study

机译：对比诱导的缺血性脑卒中患者血管造影血管造影的肾病：戏弄研究

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Goal: Computed tomography angiography (CTA) is a well-tolerated, noninvasive study of the intracranial vascular circulation; however, contrast-induced nephropathy (CIN) has been reported in 5%-7% of patients undergoing CTA. Limited studies have evaluated the risks of CIN in patients undergoing CTA. Our study was designed to evaluate the prevalence and risk factors for CIN in patients with ischemic stroke who receive a CTA. Materials and Methods: Single-center, nested, case-control study of patients with ischemic stroke who received a CTA between June 18, 2012 and January 1, 2016. Patients were grouped based on development of CIN. Findings: A total of 209 patients were included in the final analysis (178 controls, 31 cases). The prevalence of CIN during the time period studied was 14.8% (95% confidence interval [CI]: 10.2-20.2). A higher proportion of patients who developed CIN had a history of diabetes mellitus (37 [20.56%1 versus 15 [48.39%1; P = .0009) and reported taking no medications prior to admission (35 [19.44%1 versus 11 [35.48%1; P = .0458). However, a lower proportion of patients who developed CIN had a history of smoking (59 [32.78] versus 3 [9.681; P = .0091). After statistical adjustment, only a history of diabetes (odds ratio [OR] 4.15 [95% CI: 1.765, 9.754), taking no medications prior to admission (OR 3.56 [95% CI: 1.417, 8.9411) and a self-reported history of smoking (OR 0.204 [95% CI: 0.057, 0.7211) remained associated with the development of CIN. Conclusions: Those patients with a history of diabetes mellitus or not taking medications prior to admission should be monitored closely for the development of contrast-induced nephropathy CIN.
机译：目标：计算机断层造影血管造影（CTA）是对颅内血管循环的耐受性的，无侵入性研究;然而，据报告了对比诱导的肾病（CIN）以5％-7％的CTA患者报告。有限的研究已经评估了CTA患者的CIC风险。我们的研究旨在评估接受CTA的缺血性卒中患者的患病率和危险因素。材料和方法：在2012年6月18日和2016年1月1日期间接受了缺血性卒中患者的单中心，嵌套，病例对照研究。患者是基于CIN的发展进行分组的。调查结果：最终分析中共有209名患者（178例，31例）。研究期间Cin的患病率为14.8％（95％置信区间[CI]：10.2-20.2）。患有糖尿病史（37 [20.56％1与15）的历史，并报告在入院前服用药物（35 [19.44％，1月11日[35.48，[35.48（35.48） ％1; p = .0458）。然而，开发CIN的患者的较低比例的吸烟历史（59 [32.78]与3 [9.681; p = .0091）。经过统计调整后，只有糖尿病史（差距[或] 4.15 [95％CI：1.765,9.754），在入院前服用任何药物（或3.56 [95％CI：1.417,8.9411）和自我报告的历史吸烟（或0.204 [95％CI：0.057,0.7211）与CIN的开发相关。结论：糖尿病患者患有糖尿病患者，应在入院前服用药物，以密切监测对比诱导的肾病CIN。

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