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首页> 外文期刊>Journal of stroke and cerebrovascular diseases: The official journal of National Stroke Association >Sleep Apnea-Predictor of Functional Outcome in Acute Ischemic Stroke
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Sleep Apnea-Predictor of Functional Outcome in Acute Ischemic Stroke

机译：急性缺血性卒中功能结果的睡眠呼吸暂停剂

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Background: Sleep apnea is increasingly being recognized as 1 of the important, modifiable risk factors of stroke and cardiovascular diseases. Sleep apnea is thought to impair the functional recovery following stroke. Hence, we evaluated the patients with acute ischemic stroke for prevalence of sleep apnea and compared the functional outcomes of patients with and without sleep apnea, at 3rd month of acute ischemic stroke. Method: This study was conducted in Kasturba Medical College (KMC) hospital, Manipal, India, between May 2015 and August 2016. We included 102 consecutive patients of acute ischemic stroke with hemiplegic upper limb power of Medical Research Council (MRC) 3 or less. Sleep apnea was diagnosed in these patients using the sleep disordered Questionnaire, Berlin Questionnaire, and Epworth sleepiness scale. Functional outcome was measured using Barthel score on day 7 and at 3rd month following the onset of stroke. Result: Out of 102 patients, sleep apnea was present in 31 (30.6%) patients, more in males (67.7%) and elderly. Hypertension was present in 66.6% of patients with sleep apnea. NIHSS score at admission did not differ between the 2 groups. At 3rd month, the Barthel score calculated was better among patient with no apnea, but this was not statistically significant (P = .119). When mean Barthel score at baseline and 3rd month was calculated using repeated measure Analysis of Variance (ANOVA) between the 2 groups, gain in functional independence in no apnea group was statistically significant (P .001). Conclusion: Sleep-disordered breathing is an independent risk factor for stroke, and sleep apnea is also associated with other known stroke risk factors like hypertension. In acute ischemic stroke, sleep apnea has a negative impact on functional recovery. Sleep apnea is amenable to treatment and should be considered in patients with acute ischemic stroke to improve the chance of recovery, and to reduce the risk of recurrence.
机译：背景：睡眠呼吸暂停越来越多地被认可为中风和心血管疾病的重要性，可变性危险因素。睡眠呼吸暂停被认为损害中风后的功能恢复。因此，我们评估了急性缺血性卒中患者患有睡眠呼吸暂停的患病率，并在第3个月的急性缺血性卒中比较了患者的功能性结果和没有睡眠呼吸暂停的功能结果。方法：本研究在2015年5月至2016年5月至2016年5月之间在曼帕普加医学院（KMC）医院（KMC）医院进行。我们将连续102名急性缺血性卒中患者包括医学研究委员会（MRC）3或更低的偏瘫患者。使用睡眠紊乱的问卷，柏林调查问卷和欧洲呼吸睡眠量表，睡眠呼吸暂停被诊断出患者。在卒中开始后第7天和第3个月，使用条形分数测量功能结果。结果：在102例患者中，睡眠呼吸暂停存在于31例（30.6％）患者中，男性更多（67.7％）和老年人。睡眠呼吸暂停的66.6％的患者中存在高血压。入场的NIHSS分数在2组之间没有区别。在第3个月，在没有呼吸暂停的患者中计算的条形分数好，但这在统计学上没有统计学意义（p = .119）。当使用两组之间的反复测量分析（ANOVA）的反复测量分析来计算基线和第3个月的平均条形点，在没有呼吸暂停组中的功能独立性的增益在统计学上显着（P <.001）。结论：睡眠无序呼吸是中风的独立危险因素，睡眠呼吸暂停也与高血压等其他已知的中风危险因素有关。在急性缺血性卒中中，睡眠呼吸暂停对功能恢复产生负面影响。睡眠呼吸暂停适合治疗，应在急性缺血性卒中患者中考虑，以改善恢复的机会，并降低复发风险。

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