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首页> 外文期刊>Journal of stroke and cerebrovascular diseases: The official journal of National Stroke Association >The Fate of Acute Lacunar Lesions in Terms of Shape and Size
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The Fate of Acute Lacunar Lesions in Terms of Shape and Size

机译：在形状和尺寸方面的急性格术病变的命运

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Background: The description of lacunar infarcts on imaging is widely variable. In particular, there are fewer agreements on lacunar lesion size and the presence of cavitation. In this regard, we investigated the changes in size and shape of acute ischemic lesion that is possibly considered as small vessel occlusion on long-term follow-up. Methods: Patients with acute single subcortical ischemic lesion on penetrating arterial territories and without definite cause of cardioembolism and large vessel disease were included. Magnetic resonance imaging (MRI) was performed during an acute stroke period and approximately 1 year after the stroke. Maximal diameters on diffusion-weighted image and on follow-up (T2 or fluid attenuation inversion recovery) were measured. The change in lesion diameter over time was analyzed. Regarding the change in shape, lacunar lesions on follow-up were classified as either "disappeared," "cavitated," or " white matter lesion." Results: A total of 64 patients were included. The mean age was 64.94 +/- 11.29 years and 32 patients were male. The mean time interval between initial and followup MR scan was 23.39 +/- 14.88 months. The mean diameter of acute lacunar lesion was 14.11 +/- 5.77 mm. On follow-up, the mean diameter reduced to 7.76 +/- 5.19 mm. The mean percentage of final diameter over initial diameter was 53.57 +/- 26.45%. All of the lesions were less than 15 mm on follow-up. Regarding the shape of the lesion on follow-up, the lesions of 33 (51.6%) patients remained cavitated, the lesions of 14 (21.9%) patients remained as white matter lesions, and the lesions of 17 (26.6%) patients disappeared. There were no differences on clinical characteristics between patients with cavitation and those without. Conclusions: The diameter of acute lacunar lesions on initial diffusion-weighted MRI was markedly reduced on follow-up. In 52% of the patients, acute lacunar lesions were cavitated.
机译：背景：成像仪表梗死的描述是广泛的变化。特别是，在花格拉内病变尺寸和空化的存在下存在较少的协议。在这方面，我们研究了急性缺血性病变的大小和形状的变化，可能被认为是长期随访的小血管闭塞。方法：包括急性单一皮质缺血性病变针对穿透动脉领土的患者，无明确的心脏栓塞和大血管疾病。磁共振成像（MRI）在急性中风期和中风后约1年进行。测量扩散加权图像上的最大直径和随访（T2或流体衰减反转恢复）。分析了病变直径随时间的变化。关于形状的变化，随访时的裂变病变被归类为“消失”，“空化”或“白质病变”。结果：共有64名患者。平均年龄为64.94 +/- 11.29岁，32例患者是男性。初始和后续MR扫描MR扫描之间的平均时间间隔为23.39 +/- 14.88个月。急性曲形裂变病变的平均直径为14.11 +/- 5.77mm。在随访时，平均直径减少到7.76 +/- 5.19 mm。初始直径上最终直径的平均百分比为53.57 +/- 26.45％。随访的所有病变小于15毫米。关于随访时病变的形状，33（51.6％）患者的病变仍然存在空气，病变为14（21.9％）患者作为白质病变，17例（26.6％）患者的病变消失。空化患者与患者之间的临床特征没有差异。结论：随访时，初始扩散加权MRI上的急性凝集裂变病变的直径明显减少。在52％的患者中，急性凝集裂变病变被空隙。

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