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首页> 外文期刊>Journal of stroke and cerebrovascular diseases: The official journal of National Stroke Association >Changes in Quadriceps Muscle Thickness, Disease Severity, Nutritional Status, and C-Reactive Protein after Acute Stroke
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Changes in Quadriceps Muscle Thickness, Disease Severity, Nutritional Status, and C-Reactive Protein after Acute Stroke

机译：急性中风后血管肌厚度，疾病严重程度，营养状况和C反应蛋白的变化

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Background: Lower leg muscle wasting is common in stroke patients; however, patient characteristics in the acute phase are rarely studied. This study aimed to examine the relationship between changes in quadriceps muscle thickness and disease severity, nutritional status, and C-reactive protein (CRP) levels after acute stroke. Methods: Thirty-one consecutive patients with acute intracerebral hemorrhage or ischemic stroke had quadriceps muscle thickness measured in the paretic and nonparetic limbs within 1 week after admission (first week) and 2 weeks after the first examination (last week) using ultrasonography. We also determined the relationship between the percentage change in muscle thickness and disease severity, nutritional status, and CRP levels on admission. Results: There was a significant correlation between changes in muscle thickness for both paretic and nonparetic sides and National Institutes of Health Stroke Scale (NIHSS) scores (paretic limb: r = -.46, P = .01; nonparetic limb: r = -.54, P = .002, respectively); however, there was no significant correlation with nutritional status on admission. Quadriceps muscle thickness was reduced more in the CRP-positive (>=.3 mg/dL) patients than in the CRP-negative (<.3 mg/dL) patients in the nonparetic limb (positive: -21.4 +/- 12.1, negative: -11.4 +/- 16.4%; P = .039), but not in the paretic limb (positive: -23.4 +/- 9.0, negative: -19.1 +/- 15.7; P = .27). Conclusions: A high NIHSS score and a positive CRP on admission were both significantly correlated with decreased quadriceps muscle thickness after acute stroke. Nutritional status on admission was not correlated with changes in quadriceps muscle thickness for these patients.
机译：背景：小腿肌肉浪费在中风患者中是常见的;然而，很少研究急性期的患者特征。本研究旨在审查急性中风后Quaddriceps肌厚度和疾病严重程度，营养状态和C反应蛋白（CRP）水平之间的关系。方法：连续急性脑内出血或缺血性卒中的三十一点患者在入院（第一周）和第一次检查后的第一次检查后2周内测量渐进剂肌肉厚度，在瘫痪和非患肢中测量，并使用超声检查（上周）。我们还确定了肌肉厚度和疾病严重程度，营养状况和CRP水平之间的关系。结果：对瘫痪和非闭合侧的肌肉厚度和国家卫生卒中量表（NIHSS）分数的变化之间存在显着相关性（Paretic Limb：R = -.46，P = .01;非肢体肢：R = - .54，p = .002分别）;但是，与入学内没有明显的营养状况相关。 CRP阳性（> = 3mg / dL）患者中Quaddriceps肌肉厚度比在非患肢中的CRP阴性（<.3mg / dL）患者中减少（阳性：-21.4 +/- 12.1，阴性：-11.4 +/- 16.4％; p = .039），但不在垂直肢体（阳性：-23.4 +/- 9.0，阴性：-19.1 +/- 15.7; p = .27）。结论：高NIHSS得分和入院阳性CRP与急性中风后的Quaddriceps肌厚度显着相关。入院的营养状况与这些患者的Quadriceps肌厚度的变化无关。

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