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首页> 外文期刊>Journal of stroke and cerebrovascular diseases: The official journal of National Stroke Association >Comparative Risks of Ischemic Stroke in Atrial Flutter versus Atrial Fibrillation
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Comparative Risks of Ischemic Stroke in Atrial Flutter versus Atrial Fibrillation

机译：心房颤动中缺血性卒中的比较风险与心房颤动

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Introduction: The aim of this study was to compare the risk of ischemic stroke in patients who have atrial fibrillation and patients who have atrial flutter. Methods: Using inpatient and outpatient Medicare claims data from 2008 to 2014 for a 5% sample of all beneficiaries 66 years of age or older, we identified patients diagnosed with atrial fibrillation and those diagnosed with atrial flutter. The primary outcome was ischemic stroke. In the primary analysis, patients with atrial flutter were censored upon converting to fibrillation; in a secondary analysis, they were not. Survival statistics were used to compare incidence of stroke in patients with flutter and patients with fibrillation. Cox proportional hazards analysis was used to compare the associations of flutter and fibrillation with ischemic stroke after adjustment for demographics and risk factors. Results: We identified 14,953 patients with flutter and 318,138 with fibrillation. During a mean follow-up period of 2.8 (+/- 2.3) years, we identified 18,900 ischemic strokes. The annual incidence of ischemic stroke in patients with flutter was 1.38% (95% confidence interval [CI] 1.22%-1.57%) compared with 2.02% (95% CI 1.99%-2.05%) in patients with fibrillation. After adjustment for demographics and stroke risk factors, flutter was associated with a lower risk of stroke compared with fibrillation (hazard ratio .69; 95% CI .60-.79, P .05). Within 1 year, 65.7% (95% CI 64.9%-66.4%) of patients with flutter converted to fibrillation but remained at a lower risk of ischemic stroke (hazard ratio .85; 95% CI .78-.92). Conclusions: Patients with atrial flutter faced a lower risk of ischemic stroke than patients with atrial fibrillation.
机译：介绍：本研究的目的是比较患者缺血性脑卒中的风险，具有心房颤动和心房颤动的患者。方法：使用2008年至2014年的住院和门诊医疗保险索赔数据，适用于66岁或以上的所有受益人的5％样本，我们发现诊断出心房颤动的患者和被诊断患有心房颤动的患者。主要结果是缺血性卒中。在初步分析中，在转换成纤丝时被察觉心房颤动的患者;在次要分析中，他们不是。存活统计用于比较颤动患者中风的发病率和颤动患者。 Cox比例危害分析用于比较振动和颤动在调整人口统计和危险因素后与缺血性卒中的关联。结果：我们鉴定了14,953名扑腾患者和318,138患者。在平均后续期间为2.8（+/- 2.3）年，我们确定了18,900人的缺血性抚摸。颤动患者缺血性卒中的年发病率为1.38％（95％置信区间[CI] 1.22％-1.57％），患者有纤维化患者的2.02％（95％CI 1.99％-2.05％）。在调整人口统计和行程危险因素后，与颤动（危险比例为0.69; 95％CI.60-.79，P＆ 0.05），扑除与中风的风险较低。在1年内，65.7％（95％CI 64.9％-66.4％）血液转化为颤动，但缺血性卒中风险较低（危险比.85; 95％CI .78-.92）。结论：心房颤动的患者面临缺血性卒中的风险低于心房颤动的患者。

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