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首页> 外文期刊>Journal of stroke and cerebrovascular diseases: The official journal of National Stroke Association >A Correlational Study on Cerebral Microbleeds and Carotid Atherosclerosis in Patients with Ischemic Stroke
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A Correlational Study on Cerebral Microbleeds and Carotid Atherosclerosis in Patients with Ischemic Stroke

机译：缺血性脑卒中患者脑微微对脑微微型和颈动脉粥样硬化的相关性研究

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Purpose: This study aimed to investigate the correlation between cerebral microbleeds and carotid atherosclerosis in patients with ischemic stroke. Subjects and Methods: Patients with ischemic stroke treated in a hospital in China from 2016 to 2017 were enrolled in the study. Based on the results from susceptibility-weighted imaging, the patients were divided into cerebral microbleed and noncerebral microbleed groups. The degree of carotid atherosclerosis was assessed with carotid intima-media thickness (CIMB) and Crouse score of carotid plaque. The details of patients' demographic information, cerebrovascular disease-related risk factors, carotid atherosclerosis indices, cerebral microbleed distribution, and grading were recorded, compared, and analyzed. Results: Logistic regression analysis of the 198 patients showed that CIMB and Crouse score were significantly correlated with the occurrence of cerebral microbleeds. The CIMB thickening group (P = .03) and the plaque group (P = .01) were more susceptible to cerebral microbleeds. In the distribution of cerebral microbleed sites, Crouse scores were the highest in the mixed group and showed a statistically significant difference (P .01). As the degree of carotid atherosclerosis increased, the average number of cerebral microbleeds also increased (P .01). The receiver operating characteristic curve analysis of the carotid atherosclerosis indices showed a statistically significant difference. The CIMB value combined with the Crouse score was the best indicator (P .01). Conclusion: In patients with ischemic stroke, cerebral microbleeds are closely related to carotid atherosclerosis. Active control of carotid atherosclerosis is important to prevent cerebral microbleeds in patients with ischemic stroke.
机译：目的：本研究旨在探讨在缺血性卒中患者脑微出血与动脉粥样硬化之间的相关性。对象和方法：自2016年在中国的一家医院治疗至2017年缺血性中风患者的研究对象。基于从磁化率加权成像的结果，将患者分为脑微出血和非脑微出血的基团。动脉粥样硬化中评估与颈动脉内膜 - 中膜厚度（CIMB）和克劳斯度得分颈动脉斑块。病人的人口统计信息，脑血管疾病相关的危险因素，动脉粥样硬化指数，脑微出血的分布和分级的详细记录，比较和分析。结果：在198例患者的Logistic回归分析表明，CIMB和Crouse积分与脑微出血的发生均显著相关。该CIMB增稠组（P = 0.03）和斑块组（P = 0.01）为以脑微出血更敏感。脑微出血位点的分布，克劳斯得分均在混合组最高，表现出统计学显著差异（P＆LT; 0.01）。由于动脉粥样硬化的程度增加，脑微出血的平均数目也增加（P＆LT; 0.01）。接收器操作所述动脉粥样硬化指数的特性曲线分析显示有统计学差异显著。所述CIMB值与Crouse积分组合是最好的指示器（P＆LT; 0.01）。结论：在缺血性卒中患者，脑微出血密切相关的动脉粥样硬化。动脉粥样硬化的主动控制是很重要的，以防止脑微出血患者的缺血性中风。

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