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首页> 外文期刊>Journal of stroke and cerebrovascular diseases: The official journal of National Stroke Association >Acute Ischemic Stroke with Vessel Occlusion-Prevalence and Thrombectomy Eligibility at a Comprehensive Stroke Center
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Acute Ischemic Stroke with Vessel Occlusion-Prevalence and Thrombectomy Eligibility at a Comprehensive Stroke Center

机译：急性缺血性卒中血管闭塞 - 血液切除率和血液切除术在综合冲程中心

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Introduction: Endovascular thrombectomy (ET) for acute ischemic stroke (AIS) caused by large vessel occlusion (LVO) can prevent severe disability and mortality. There is currently limited data on the epidemiology of LVO strokes and ET eligibility. We aim to determine the incidence of intracranial vessel occlusion (IVO) strokes eligible for ET per 2018 American Heart Association (AHA) guidelines and characteristics of an AHA ineligible population at a comprehensive stroke center (CSC). Methods: Retrospective chart review of all consecutive AISs at a CSC between November 2014 and February 2017. Demographic, clinical, and radiographic data were analyzed to determine ET eligibility per AHA guidelines and characteristics of ineligible patients were investigated. Results: Twenty-four percent of AIS harbor an IVO. Thirty percent of IVO strokes and 47% of anterior circulation LVO strokes are thrombectomy eligible per AHA guidelines. Most common reasons for thrombectomy ineligibility among IVO strokes are presence of IVO other than anterior circulation LVO (35%, n = 224), presence of large stroke burden (15%, n = 93), baseline modified Rankin scale greater than or equal to 2 (14%, n = 89), and NIHSS score less than 6 (15%, n = 96). Conclusions: At a CSC, 1 in 4 AISs harbor an IVO. Seven in 100 acute ischemic strokes, 3 in 10 strokes with vessel occlusion, and 1 in 2 strokes with internal carotid or middle cerebral artery M1 occlusion are thrombectomy eligible per AHA 2018 guidelines. These data highlight that current guidelines render a majority of strokes thrombectomy ineligible and a large window of opportunity exists for clinical investigation.
机译：介绍：由大容器闭塞（LVO）引起的急性缺血性卒中（AIS）的血管内血栓切除术（ET）可以防止严重的残疾和死亡率。目前有关于LVO笔画的流行病学数据有限的数据。我们的目标是确定颅内血管闭塞（IVO）中风的发病率，符合2018年美国心脏协会（AHA）的综合行程中心（CSC）的AHA没有资格的人口的准则和特征。方法：2014年11月和2017年2月在CSC之间的回顾性审查。分析人口统计学，临床和放射线数据，以确定每个AHA指南的ET资格，还有不合格患者的特征。结果：二十四个AIS覆盖IVO。百分之三的IVO中风和47％的前循环LVO卒中是每个AHA指南的血栓切除术。 IVO中风中血栓切除术的最常见的原因是前循环LVO（35％，N = 224）以外的IVO存在，大冲程负荷（15％，n = 93），基线改变Rankin规模大于或等于2（14％，n = 89），NIHS得分小于6（15％，n = 96）。结论：在一个CSC，1英寸AISS HARBOR HARBOR IVO。七次急性缺血性卒中，3分10例血管闭塞，1英寸颈动脉内或中脑动脉M1闭塞的1分，是每AHA 2018指南的血液切除术。这些数据突出显示当前指南呈现大多数笔触血栓切除术不合格，并且存在临床调查的大型机会窗口。

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