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首页> 外文期刊>Journal of stroke and cerebrovascular diseases: The official journal of National Stroke Association >Features of Patients Aged 80 Years or Older with Embolic Stroke of Undetermined Source
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Features of Patients Aged 80 Years or Older with Embolic Stroke of Undetermined Source

机译：80岁或以上患者栓塞潜伏的患者的特征

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Background: Embolic stroke of undetermined source has not been thoroughly investigated in older patients. In this study, we investigated the features of this condition in patients greater than or equal to 80 years of age. Methods: All patients with acute ischemic stroke in our hospital underwent diffusion-weighted imaging, magnetic resonance angiography, T2-weighted imaging, and fluid-attenuated inversion recovery sequence imaging. Embolic stroke of undetermined source was defined as a radiologically confirmed nonlacunar brain infarct on diffusion-weighted imaging without (1) extracranial or intracranial atherosclerosis causing greater than or equal to 50% luminal stenosis in arteries supplying the ischemic area, (2) major-risk cardioembolic source, and (3) any other specific cause of stroke. We retrospectively identified consecutive patients hospitalized for acute ischemic stroke who met the embolic stroke of undetermined source diagnostic criteria and investigated patients' baseline and diagnostic findings. Results: We divided 122 consecutive embolic stroke of undetermined source patients (median age: 73 years; 49 men, 73 women) into 2 groups by age at admission. Patients aged greater than or equal to 80 years had higher D-dimer and brain natriuretic peptide levels, more frequent premature atrial complexes/day in 24-hour Holter electrocardiography, and thicker maximum intima media thickness on ultrasound compared with patients aged less than 80 years (P .05, U test). Conclusions: Our results suggest that high admission D-dimer and brain natriuretic peptide levels are associated with age of onset in patients with embolic stroke of undetermined source. Patients aged greater than or equal to 80 years tended to have more frequent premature atrial complexes and thicker maximum intima media thickness compared with patients aged less than 80 years.
机译：背景：老年患者尚未彻底调查未确定源的栓塞中风。在这项研究中，我们研究了大于或等于80岁的患者的这种情况的特征。方法：所有急性缺血性中风的患者在我们院内接受扩散加​​权成像，磁共振血管造影，T2加权成像和流体衰减的反转恢复序列成像。未确定源的栓塞卒中被定义为在扩散加权成像上的放射学证实的非裂变脑梗塞，没有（1）颅外或颅内动脉粥样硬化导致提供缺血区域的动脉的大于或等于50％的腔静脉曲张，（2）主要风险心电图源，（3）中风的任何其他特定原因。我们回顾性地确定了住院治疗急性缺血性卒中的连续患者，符合未确定的源诊断标准和调查患者基线和诊断结果的栓塞中风。结果：我们将122例连续栓塞中风分开（中位数：73岁; 49名男子，73名女性）进入2组。大于或等于80年的患者具有较高的D-二聚体和脑利钠肽水平，24小时半月内心电图中更频繁的过早性心房复合物，以及超声波的最大最大内膜介质厚度与少于80年的患者相比（P＆ 05，U测试）。结论：我们的研究结果表明，高录取D-二聚体和脑利钠肽水平与未确定源栓塞患者的发病年龄有关。患者大于或等于80岁的患者往往具有更频繁的过度心房络合物和较厚的最大内膜介质厚度，与少于80岁的患者相比。

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