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首页> 外文期刊>Journal of studies on alcohol and drugs. >Universal or targeted screening for fetal alcohol exposure: a cost-effectiveness analysis.
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Universal or targeted screening for fetal alcohol exposure: a cost-effectiveness analysis.

机译：胎儿酒精暴露的普遍或有针对性的筛选：成本效益分析。

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OBJECTIVE: In this article, we compared the costs of testing meconium for alcohol exposure in newborns with the lifetime benefits of early detection and intervention. METHOD: A decision analytic model was developed to assess the cost-effectiveness of testing meconium for two scenarios: (1) all infants in the Canadian province of Ontario and (2) infants who have an older sibling diagnosed with fetal alcohol spectrum disorder (FASD). The model incorporated the costs of early screening, early intervention, and the lifetime societal benefits of early intervention. RESULTS: The cost of the meconium test is Can. Dollars 150. The lifetime societal cost of the disease is Can. Dollars 1.3 million per incident case. The benefit of early intervention is an improvement in literacy, which improves the quality of life parameter by 0.17 and increases adult lifetime earnings by Dollars 26,400 per year. The ratio of the incremental cost to the incremental benefits results in an incremental cost-effectiveness ratio for mandating a universal screen of all newborns in Ontario of Dollars 65,874 per quality-adjusted life years. When considering targeted screening, there is a cost savings for society and improvements in quality of life. CONCLUSIONS: Depending on society's willingness-to-pay threshold for improving infants' lives in a setting of considerable equity concerns, universal screening and targeted screening of infants who have an older sibling diagnosed with FASD both represent policies that are good value for the money.
机译：目的：在本文中，我们比较了新生儿中酒精暴露的粉末暴露的成本与早期检测和干预的寿命益处。方法：制定了决策分析模型，以评估两种情况的测试Mechium的成本效益：（1）安大略省加拿大省的所有婴儿和（2）婴儿患有胎儿酒精谱紊乱的较大兄弟姐妹（FASD ）。该模型纳入了早期筛选，早期干预和早期干预的终身社会效益的成本。结果：MeConium测试的成本可以。美元150.疾病的终身社会成本可以。每件事案例130万美元。早期干预的好处是识字性的提高，这提高了生活质量参数0.17，每年增加26,400美元的成人终身收益。增量成本与增量效益的比率导致增量成本效益比，以便在每年调整的终身年度65,874美元中的Ontario中授权所有新生儿的普遍筛查。在考虑有针对性的筛查时，社会的成本节约和生活质量的改进。结论：根据社会愿意为改善婴儿的愿望的愿望，在制定相当的股权问题，普遍筛查和针对性筛查患有FASD的较大兄弟姐妹的婴儿的生活中，这两者都代表了物有所值的政策。

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