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首页> 外文期刊>Journal of substance abuse treatment >Mortality trends among heroin users treated between 1975 and 2013 in Northern Italy: Results of a longitudinal study
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Mortality trends among heroin users treated between 1975 and 2013 in Northern Italy: Results of a longitudinal study

机译：在意大利北部1975年至2013年间治疗海洛因用户的死亡趋势：纵向研究的结果

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Abstract Background The aim of this study was to examine heroin mortality trends and changes in causes of death, across time and age, in a cohort of the heroin population of treated. Methods 5899 subjects attending twelve centers for addiction treatment (SERT) in north Italy following problems due to heroin abuse between 1975 and 2013 were recruited. Results This study documented elevated mortality among subjects with primary heroin abuse, with an elevated death risk in all the classes of age, declining until 2009 ad increasing starting from 2010. AIDS was the first cause of death, followed by overdose and liver-related diseases. In the course of time mortality for AIDS and for drug-related deaths has declined, whereas liver mortality and all tumors mortality have risen over time, becoming the most common causes of death by the end of the follow up. As compared with the general population, the excess mortality (SMR) observed for all causes in either sex was 13.2, higher in females (SMR = 21.5) as compared with males (SMR = 12.1). Higher SMRs were found in 25/34 age-group patients, with a progressive decrease in subjects with age 34 years. Conclusions In the course of time, among heroin users, mortality and the causes of death have changed; for SERT clients special attention should be paid to the prevention and treatment of liver-related diseases. Highlights ? This study documented elevated mortality among subjects with primary heroin abuse, declining until 2009 ad increasing starting from 2010. ? Liver mortality and all tumors mortality have risen over time, becoming the most common causes of death by the end of the follow up. ? Problems emerge correlated to the aging of the users of the addiction services and to the alterations in the characteristics of the new accesses. ? The rise in the excess mortality in respect to the general population is also connected to the socio-economic condition of many heroin addicts.
机译：摘要背景这项研究的目的是在海洛因群体的群组中，检查海洛因死亡率趋势和死亡原因的变化，跨越治疗的海洛因群体。方法招募了5899例，招聘了1975年至2013年间北方北部成瘾治疗（SERT）的十二个科目（SERT）。结果本研究记录了主要海洛因滥用的受试者的死亡率提高，所有年龄的死亡风险升高，直到2009年从2010年开始增加。艾滋病是死亡的第一个死因，其次是过量和肝脏有关的疾病。在艾滋病和与毒品相关的死亡的时期死亡率下降，而肝脏死亡率和所有肿瘤的死亡率随着时间的推移而上升，成为后续结束的最常见的死亡原因。与一般人群相比，与男性相比在25/34岁的患者中发现了较高的SMR，患有年龄和GT的受试者的逐步减少; 34年。结论在一段时间内，海洛因用户，死亡率和死亡原因发生了变化;对于Sert客户来说，应特别注意预防和治疗肝脏有关的疾病。强调 ？本研究记录了主要海洛因滥用的受试者的死亡率提高，直到2009年从2010年开始增加。肝脏死亡率和所有肿瘤死亡率随着时间的推移而上升，成为后续结束的最常见的死因。还问题出现与成瘾服务用户的老化以及新访问的特征的改变相关。还对一般人群的过度死亡率的增加也与许多海洛因成瘾者的社会经济状况有关。

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