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首页> 外文期刊>Journal of substance abuse treatment >Beliefs about the consequences of using benzodiazepines among persons with opioid use disorder
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Beliefs about the consequences of using benzodiazepines among persons with opioid use disorder

机译：关于使用阿片类药物使用障碍的人群使用苯并二氮杂卓的后果的信念

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Abstract Background Patients admitted to addiction treatment programs report high rates of concurrent opioid and benzodiazepine (BZD) use. This combination places individuals at high risk for accidental overdose and other serious consequences. However, little is known about the beliefs opioid users have about the consequences of BZD use. Methods We surveyed consecutive persons initiating inpatient opioid detoxification (N = 476; 95.0% enrollment) and identified 245 who reported BZD use in the past 30 days and/or had a positive toxicology. We compared those who did and did not report BZD use on demographic and substance use variables, and specific beliefs about the potential effects of BZDs. Results Participants averaged 32.2 years of age, 71.2% were male, 86.6% used heroin, and 68.7% reported injection drug use in the past 30 days. Over half (51.5%) used a BZD in the month prior to admission; of these, 26.2% (n = 64) reported being prescribed a BZD. Alprazolam (Xanax) was the most commonly used BZD (54%). Benzodiazepine users (versus non-users) were significantly more likely to be female and non-Hispanic White, use concurrent substances, and report past year overdose. Overall, nearly all BZD users endorsed accurate beliefs that BZDs can increase the risk of overdose and can be addictive. However, BZD users, relative to non-users, were significantly less likely to endorse some known adverse consequences of BZDs, such as risk of worsening depression and poor medication-assisted opioid treatment retention. Conclusions Delineating the full array of risks from combining BZDs and opioids should be a high priority in detoxification settings, given the increased risks associated with BZD misuse in this population. Highlights ? Over half of persons initiating inpatient opioid detoxification used a BZD in the prior month. ? BZD users (versus non-users) were more likely to be female and non-Hispanic White. ? BZD users (versus non-users) were more likely to report use of concurrent substances and past year overdose. ? Overall, BZD users accurately perceived the risks of BZD use. ? BZD users were less accurate than non-BZD users with respect to some BZD-related consequences.
机译：摘要背景患者允许成瘾治疗方案报告高速同时阿片类药物和苯二氮卓（BZD）使用。这种组合使个人处于偶然过量和其他严重后果的高风险。然而，关于表阿片类药物的信仰用户对BZD使用的后果知之甚少。方法，我们将连续进行调查，从而启动住院性阿片类药物排毒（N = 476; 95.0％的注册），并确定了在过去30天和/或具有阳性毒理学中的BZD使用的245名。我们比较了那些已经做过的人并没有向人口统计和物质使用变量报告BZD使用，以及关于BZDS潜在影响的具体信念。结果参与者平均为32.2岁，71.2％是男性，86.6％使用海洛因，报告的68.7％在过去30天内使用注射药物。超过一半（51.5％）在入学前的月份使用了BZD;其中，报告了26.2％（n = 64）被规定的BZD。 Alprazolam（Xanax）是最常用的BZD（54％）。 Benzodiazepine用户（与非用户）更有可能是女性和非西班牙裔白人，使用并发物质，并报告过去的过量。总体而言，几乎所有BZD用户都赞同准确的信念，即BZDS可以增加过量的风险，并且可能是令人上瘾的。然而，相对于非用户的BZD用户显着不太可能赞同BZDS的一些已知的不良后果，例如恶化抑郁症的风险和差的药物辅助阿片治疗保留。结论划定基于BZDS和阿片类药物的完整风险阵列应该是排毒环境中的高优先级，因为与本群体中的BZD滥用相关的风险增加。强调 ？超过一半的人发起住院表阿片类药物排毒在上个月中使用了BZD。还BZD用户（与非用户）更有可能成为女性和非西班牙裔白人。还BZD用户（与非用户）更有可能报告使用并发物质和过去的一年过量。还总体而言，BZD用户准确地发现了BZD使用的风险。还BZD用户比非BZD相关后果不如非BZD用户的准确性。

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