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首页> 外文期刊>Journal of the International Neuropsychological Society: JINS >A Positive Relationship between Cognitive Reserve and Cognitive Function after Stroke: Dynamic Proxies Correlate Better than Static Proxies
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A Positive Relationship between Cognitive Reserve and Cognitive Function after Stroke: Dynamic Proxies Correlate Better than Static Proxies

机译:中风后认知储备与认知功能之间的正关系:动态代理比静态代理更好地相关

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Objectives: How brain damage after stroke is related to specific clinical manifestation and recovery is incompletely understood. We studied cognitive reserve (CR) in stroke patients by two types of measurements: (i) objectively verifiable static proxies (i.e., education, occupational attainment), and (ii) subjective, dynamic proxies based on patient testimony in response to a questionnaire. We hypothesized that one or both of these types of CR measurements might correlate positively with patient cognitive performance during the post-acute and chronic phases of recovery. Method: Thirty-four stroke patients underwent neuropsychological assessment at 2, 6 and 24 months after stroke onset. In chronic stage at 24+ months, self-rating assessments of cognitive performance in daily life and social integration were obtained. CR before and after stroke was estimated using static proxies and dynamic proxies were obtained using the Cognitive Reserve Scale (CRS-Pre-stroke, CRS-Post-stroke). Results: CRS-Pre-stroke and CRS-Post-stroke showed significant mean differences. Dynamic proxies showed positive correlation with self-assessment of attention, metacognition, and functional ability in chronic stage. In contrast, significant correlations between static proxies and cognitive recovery were not found. Conclusions: Dynamic proxies of CR were positively correlated with patients’ perception of their functional abilities in daily life. To best guide cognitive prognosis and treatment, we propose that dynamic proxies of CR should be included in neuropsychological assessments of patients with brain damage.
机译:目标:中风后脑损伤是如何与特定临床表现相关的,并且不完全理解恢复。我们通过两种测量研究了中风患者的认知储备(CR):(i)客观可核实的静态代理(即,教育,职业达到)和(ii)基于患者证词的主观动态代理,以回应问卷。我们假设这些类型的CR测量中的一种或两种可能在急性和慢性阶段的回收率期间与患者认知性能具有相关性。方法:34例中风患者在中风发作后2,6和24个月内接受神经心理学评估。在24多个月的慢性阶段,获得了日常生活和社会融合中的认知性能的自评认知性能的自我评估评估。使用静态代理估计中风之前和后,使用认知储备秤(CRS-Preks,Crs-后行程)获得动态代理。结果:CRS-pre-introke和CRS-后卒中显示出显着的平均差异。动态代理显示与慢性阶段的关注,元认知和功能能力的自我评估正相关。相比之下,未找到静态代理与认知恢复之间的显着相关性。结论:CR的动态代理与日常生活中的职能能力的患者呈正相关。为了最佳指导认知预测和治疗,我们提出了CR的动态代理应包括在脑损伤患者的神经心理学评估中。

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