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首页> 外文期刊>Journal of the Dermatology Nurses’ Association >Systematic Review of the Topical Steroid Addiction and Topical Steroid Withdrawal Phenomenon in Children Diagnosed With Atopic Dermatitis and Treated With Topical Corticosteroids
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Systematic Review of the Topical Steroid Addiction and Topical Steroid Withdrawal Phenomenon in Children Diagnosed With Atopic Dermatitis and Treated With Topical Corticosteroids

机译：局部类固醇成瘾和局部类固醇戒断现象的系统审查，诊断为特应性皮炎，局部皮质类固醇治疗

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摘要

Background: A 2015 National Eczema Association study concluded that topical steroid withdrawal is an effect of prolonged, frequent use of topical steroids occurring mostly in adult women. It is unclear whether children develop topical steroid withdrawal. Objective: The aim of this study was to assess current evidence regarding topical steroid withdrawal in children. Methods: This study is a systematic review of medical literature as well as online social media sites and blogs regarding topical steroid withdrawal in children. Results: Literature search yielded zero studies on/or reporting classic topical steroid withdrawal in children; however, periorificial dermatitis, which is generally a steroid-induced disorder in children, was reported in >320 cases. Of 142 social media blogs on topical steroid withdrawal, 26 were blogs discussing children. Twenty-seven cases were included in this review. Length of topical steroid use ranged from 2 months to 12 years. Conclusions: Topical steroid withdrawal occurs in children and can result from discontinuing topical steroids used for as little as 2 months. Resultant signs/symptoms can last >12 months, even with short duration of use. Clinicians and caregivers should be aware of this possible adverse effect of topical steroids and monitor the effects of topical steroids on infants/children, but more data are needed on this condition.
机译：背景：2015年国家湿疹协会研究得出结论，局部类固醇戒断是延长，经常使用主要在成人女性中发生的局部类固醇的效果。目前尚不清楚儿童是否发展局部类固醇戒断。目的：本研究的目的是评估有关儿童局部类固醇戒断的目前的证据。方法：本研究是对医学文献的系统审查，以及关于儿童局部类固醇戒断的在线社交媒体网站和博客。结果：文献搜索产生零研究/或报告儿童经典局部类固醇戒断;然而，在> 320例案例中报道了局面性皮炎，通常是儿童类固醇诱导的病症。在142个社交媒体博客上，题目的类固醇撤回，26名是博客讨论儿童。本次审查中包含二十七种案件。局部类固醇的长度范围从2个月到12年。结论：局部类固醇戒断在儿童中发生，可能是由于常产类固醇而导致使用的局部类固醇少2个月。结果迹象/症状可以持续> 12个月，即使使用寿命短。临床医生和护理人员应该了解局部类固醇的这种可能的不良影响，并监测局部类固醇对婴儿/儿童的影响，但在这种情况下需要更多的数据。

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