...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of the Indian Chemical Society >Microwave induced conformational change and aggregation of bovine beta-lactoglobulin: An insight to non-thermal effect
【24h】

Microwave induced conformational change and aggregation of bovine beta-lactoglobulin: An insight to non-thermal effect

机译：微波诱导牛β-乳酰脱蛋白的构象变化和聚集：对非热效应的洞察

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Recent studies comprise detailed comparative studies on thermal and microwave induced non-thermal conformational changes at the secondary and tertiary level of structure of beta-lg to ensure the non-conventional heating can produce a non-thermal effect with analogous thermal range. Both the fluorescence studies and circular dichroic studies revealed the conformational changes of beta-lg SDS-PAGE study was carried out to identify the higher oligomer and the isocratic-HPLC was used to characterize the oligomer/aggregates. Morphology study with the help of FE-SEM technique was successful to identify the sphrerulitic oligomer formation during the aggregation pathway. In fact conformational change related neurodegenerative disorders such as amylopathies including Alzeimer's, Parkinsons and Creuzfeld-Jakob diseases could be envisioned in the view point of microwave induced conformational changes leading to the protein aggregation.
机译：最近的研究包括对β-LG的二次和三级结构的热和微波诱导的非热构象变化的详细比较研究，以确保非常规加热可以与类似的热距离产生非热效应。 荧光研究和圆形二色性研究揭示了β-LG SDS-PAGE研究的构象变化，以鉴定较高的低聚物，并且使用等体-HPLC用于表征低聚物/聚集体。 借助Fe-SEM技术的形态学研究是成功的，以鉴定聚集途径期间的散氏低聚物形成。 实际上，在微波诱导的构象变化的观点中，可以设想一致的改变相关的神经变化障碍，例如包括外水分，帕金森和Creuzfeld-jakob疾病，导致蛋白质聚集的视点。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号