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首页> 外文期刊>Journal of women’s health >Personalized Care in the Prevention of Treatment-Related Cardiac Dysfunction in Female Cancer Survivors
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Personalized Care in the Prevention of Treatment-Related Cardiac Dysfunction in Female Cancer Survivors

机译：在预防治疗相关的心脏功能障碍中的个性化护理，女性癌症幸存者

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Background: The American Cancer Society projects the number of U.S. cancer survivors to exceed 20 million individuals by 2026. However, approximately one in four cancer survivors report decreased quality of life due to physical dysfunction and disabling symptoms. Many effective anticancer treatments are now understood to be associated with cardiotoxicity, such that, for many survivors, the risk of death from cardiovascular disease now exceeds that of recurrent cancer. Materials and Methods: We undertook a Clinical Review of cancer treatment-related cardiac dysfunction (CTRCD) associated with standard treatment regimens with attention to risks experienced by female cancer patients and survivors. Results: Risks of standard (chemotherapy, radiotherapy) and targeted (antibodies, kinase inhibitors) in development of CTCRD in females are discussed. Multidisciplinary approaches in prevention are reviewed. Conclusions: Female cancer survivors with CTRCD represent an entirely new population at high risk of morbidity and mortality. Increased awareness of the short- and long-term effects of anti-cancer treatments is necessary for the community health care provider for early detection and CTRCD risk reduction.
机译：背景：美国癌症协会将美国癌症幸存者的数量突出2026年。然而，由于物理功能障碍和致残症状，四个癌症幸存者中的大约一中降报告。现在，许多有效的抗癌治疗将被理解为与心脏毒性有关，使得对于许多幸存者，心血管疾病死亡的风险现在超出了复发性癌症的危险。材料和方法：我们对与标准治疗方案相关的癌症治疗相关的心脏功能障碍（CTRCD）进行了临床审查，其关注女性癌症患者和幸存者经历的风险。结果：讨论了在女性中，标准（化学疗法，放疗）和靶向（抗体，激酶抑制剂）的风险讨论。综述了预防的多学科方法。结论：患有CTRCD的女性癌症幸存者在发病率和死亡率的高风险中代表了一个完全新的人口。增加对抗癌治疗的短期和长期影响的意识是社区医疗保健提供者的早期检测和Ctrcd风险减少所必需的。

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