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Efficacy of Insulin Pump Therapy on Diabetes Treatment Satisfaction and Glycemic Control Among Patients with Type 1 Diabetes Mellitus in Saudi Arabia: A Prospective Study

机译:胰岛素泵治疗沙特阿拉伯1型糖尿病患者糖尿病治疗满意度和血糖对照的疗效:一项潜在研究

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Introduction: The aim of this study was to explore the impact of insulin pump therapy on diabetes treatment satisfaction and glycemic control among patients with type 1 diabetes mellitus (T1DM) in Saudi Arabia. Methods: A 6-month, prospective study was conducted among 47 patients (aged 17–24 years) with T1DM who attended the Insulin Pump Clinic at Prince Sultan Military Medical City, Riyadh, Saudi Arabia, between April 2014 and November 2014. The respondents were purposively and conveniently selected and were interviewed using the Arabic version of the Diabetes Treatment Satisfaction Questionnaire at baseline, 3, and 6 months. Demographics and clinical variables including hemoglobin A1c (HbA1c) were also collected. Results: The mean (±standard deviation) age of the study cohort was 19.1 ± 1.93 years. Seventeen patients were male (36.2%) and 30 were female (63.8%). Compared to baseline, significant positive differences were found in treatment satisfaction among female patients and patients with long-standing T1DM at 6 months. Frequency of hyperglycemia and hypoglycemia declined significantly in female patients at 6 months and in patients who had a shorter duration of T1DM. Furthermore, significant positive differences were found in HbA1c levels among female patients and among those who had a shorter duration of T1DM compared to baseline. Both female and male patients and those with a shorter duration of T1DM showed a significant decline in insulin necessity at 6 months when compared to baseline. Conclusion: Although multiple daily injections is a feasible preference for insulin supply, insulin pumps should also be considered for patients with T1DM as it appears to increase patients’ treatment satisfaction, decrease the frequency of hypoglycemia, hyperglycemia, and reduce HbA1c levels.
机译:介绍:本研究的目的是探讨胰岛素泵治疗在沙特阿拉伯1型糖尿病(T1DM)患者中糖尿病治疗满意度和血糖控制的影响。方法:6个月,预期研究是在2014年4月和2014年11月期间参加了Sultan军事医疗城的胰岛素泵诊所的47名患者(17-24岁)的前瞻性研究。受访者有意地和方便地选择,并使用阿拉伯语版本的糖尿病治疗满意度问卷在基线,3和6个月进行了访谈。还收集了包括血红蛋白A1C(HBA1C)的人口统计和临床变量。结果:研究队列的平均值(±标准偏差)年龄为19.1±1.93岁。 17名患者是男性(36.2%)和30名是女性(63.8%)。与基线相比,女性患者的治疗满意度和6个月长期患者的治疗满意度发现了显着的正差异。在6个月和患者T1DM持续时间较短的患者中,女性患者的高血糖和低血糖症的频率显着下降。此外,女性患者中的HBA1C水平和与基线相比较短的持续时间较短的人中,发现了显着的正差异。女性和男性患者和较短的T1DM持续时间的患者显示出与基线相比6个月的胰岛素需要显着下降。结论:虽然多次每日注射是对胰岛素供应的可行偏好,但也应考虑胰岛素泵,因为它似乎增加了患者的治疗满意度,降低了低血糖,高血糖和降低HBA1C水平的频率。

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