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首页> 外文期刊>American Orthoptic Journal >The Efficacy of Botulinum Toxin Treatment for Children with a Persistent Esotropia Following Bilateral Medial Rectus Recessions and Lateral Rectus Resections
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The Efficacy of Botulinum Toxin Treatment for Children with a Persistent Esotropia Following Bilateral Medial Rectus Recessions and Lateral Rectus Resections

机译：肉毒杆菌毒素治疗儿童双侧内侧直肌凹陷和外侧直肌切除术后持续性内斜视的疗效

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Background and Purpose: To report on the outcomes of treating children with a persistent esotropia with an injection of botulinum toxin in a medial rectus muscle. Patients and Methods: The medical records were reviewed of all children at one institution with a persistent esotropia after bilateral medial rectus recessions and bilateral lateral rectus resections then treated with a botulinum toxin injection. Results: Five patients with a mean preoperative esotropia of 37~delta (range 25-50~delta) underwent bilateral medial rectus recessions and then bilateral lateral rectus resections. Their residual esotropia (mean of 25~delta; range 18-35~delta) was then treated with a single injection of 3-5 units of botulinum toxin into one medial rectus muscle. The patients were then followed for a mean of 34 months (range 14-79 months). At last follow-up, two patients had an esotropia < 10~delta. The other three patients had no long-term improvement in their ocular alignment. Two of these patients then underwent additional strabismus surgery. In both cases, they then developed a consecutive exotropia. Conclusion: Treatment with a single injection of botulinum toxin was beneficial in 2 of 5 children. Botulinum toxin treatment alone did not result in a consecutive exotropia in any patients treated.
机译：背景与目的：报告在直肌内侧注射肉毒杆菌毒素治疗持续性内斜视的儿童的疗效。患者和方法：回顾了一所机构中所有患儿的病历，这些患儿在双侧内侧直肌凹陷和双侧外侧直肌切除后再用肉毒杆菌毒素治疗后，患有持续的内斜视。结果：5例平均术前内斜率为37〜delta（范围为25-50〜delta）的患者接受了双侧内侧直肌凹陷，然后进行了双侧外侧直肌切除术。然后将其3-5小时的肉毒杆菌毒素单次注射到一条内直肌中，以治疗其残留的内斜视（平均25度，范围18-35度）。然后平均随访34个月（14-79个月）。在最后一次随访中，有两名患者的内斜视<10％。其他三名患者的眼线排列没有长期改善。这些患者中的两名随后接受了额外的斜视手术。在这两种情况下，他们都出现了连续的外斜视。结论：单次注射肉毒杆菌毒素治疗对5名儿童中的2名有益。单独的肉毒杆菌毒素治疗不会在任何接受治疗的患者中导致连续的外斜视。

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