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首页> 外文期刊>American Journal of Obstetrics and Gynecology >Measurement of hs-CRP is irrelevant to diagnose and stage endometriosis: prospective study of 834 patients
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Measurement of hs-CRP is irrelevant to diagnose and stage endometriosis: prospective study of 834 patients

机译：hs-CRP的测定与子宫内膜异位症的诊断和分期无关：对834名患者的前瞻性研究

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摘要

The pathogenesis of endometriosis is associated with an inflammatory process. Here, we assessed if the levels of high-sensitivity C-reactive protein (hs-CRP) in serum could constitute an effective method for detecting systemic inflammation during endometriosis. STUDY DESIGN: This was a prospective, laboratory-based study, which was carried out in a tertiary care university hospital. Patients with histologically proven endometriosis (n = 370) and unaffected women (n = 464) were enrolled from January 2005 through December 2009. We performed complete surgical excision of endo-metriotic lesions with pathological analysis. In addition, hs-CRP levels were determined through a particle-enhanced immunoturbidimetric method. The hs-CRP levels were measured in both controls and women with endometriosis according to the established surgical classifications of endometriosis: superficial peritoneal endometriosis, endometrioma, and deep infiltration endometriosis. Also, hs-CRP levels were evaluated according to hormonal treatment and menstrual cycle.
机译：子宫内膜异位症的发病机制与炎症过程有关。在这里，我们评估了血清中高敏C反应蛋白（hs-CRP）的水平是否可以构成检测子宫内膜异位症系统性炎症的有效方法。研究设计：这是一项基于实验室的前瞻性研究，在一家三级护理大学医院进行。从2005年1月至2009年12月，纳入经组织学证实为子宫内膜异位的患者（n = 370）和未受影响的女性（n = 464）。我们通过病理分析对子宫内膜异位病变进行了完整的手术切除。此外，通过颗粒增强免疫比浊法确定了hs-CRP水平。根据确定的子宫内膜异位症外科分类：浅层腹膜子宫内膜异位症，子宫内膜瘤和深层浸润性子宫内膜异位症，在对照组和患有子宫内膜异位症的妇女中均测量了hs-CRP水平。此外，根据激素治疗和月经周期评估了hs-CRP水平。

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